Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger
Summary. Problem. Transfusional malaria is an accidental transmission of Plasmodium via a blood transfusion. Its magnitude is underestimated and very little data on the assessment of this risk are available in Niger. Objective. This study aimed to determine the prevalence of plasmodial infection of...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/7290852 |
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| author | Aminata Iro Moustapha Mahamane Lamine Ramatoulaye Hamidou Lazoumar Ibrahim Alkassoum Daou Maman Harouna Amadou Mahaman Laouali Mahamadou Doutchi Seydou Maiguizo Ibrahim Maman Laminou |
| author_facet | Aminata Iro Moustapha Mahamane Lamine Ramatoulaye Hamidou Lazoumar Ibrahim Alkassoum Daou Maman Harouna Amadou Mahaman Laouali Mahamadou Doutchi Seydou Maiguizo Ibrahim Maman Laminou |
| author_sort | Aminata Iro |
| collection | DOAJ |
| description | Summary. Problem. Transfusional malaria is an accidental transmission of Plasmodium via a blood transfusion. Its magnitude is underestimated and very little data on the assessment of this risk are available in Niger. Objective. This study aimed to determine the prevalence of plasmodial infection of blood bags at the National Blood Transfusion Center of Niamey (NBTC). Methodology. A cross-sectional study to diagnose Plasmodium infection by microscopy and Rapid Diagnostic Test (RDT) was carried out during the rainy season (September to November 2015). Blood grouping was performed by the BETH-VINCENT technique. Results. One thousand three hundred and fifty-seven (1357) blood bags were collected. One hundred and fifty-seven (11.6%) of the donors were infected with Plasmodium by microscopy and 2.4% (9/369) by rapid diagnostic test. All infections were with P. falciparum (100%). The mean parasite density was 197 parasites/μL (SD=281; [80: 2000]). There were no significant differences in infection prevalence between the ABO blood groups (p=0.3) or the rhesus positivity (p=08). There is also no significant difference in temporal (p=0.1) and spatial (p=0.6) distribution. Conclusion. The transmission of transfusional malaria during the rainy season is a fact in Niger. Such risks were independent of the ABO blood type and positivity for the rhesus antigen. Pretransfusion diagnosis or posttransfusion therapy should be instituted to prevent it. |
| format | Article |
| id | doaj-art-030e4d4e77464874a5f4f2189eb6ca80 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-030e4d4e77464874a5f4f2189eb6ca802025-02-03T01:33:16ZengWileyJournal of Tropical Medicine1687-96861687-96942019-01-01201910.1155/2019/72908527290852Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-NigerAminata Iro0Moustapha Mahamane Lamine1Ramatoulaye Hamidou Lazoumar2Ibrahim Alkassoum3Daou Maman4Harouna Amadou Mahaman Laouali5Mahamadou Doutchi6Seydou Maiguizo7Ibrahim Maman Laminou8Faculté de Science de la Santé de l’Université de Niamey, NigerUniversité Check Anta Diop de Dakar, SenegalCentre de Recherche Médicale et Sanitaire, NigerFaculté de Science de la Santé de l’Université de Niamey, NigerFaculté de Science de la Santé de l’Université de Niamey, NigerUniversité de Maradi, NigerUniversité de Zinder, NigerCentre National de Transfusion Sanguine de Niamey, NigerCentre de Recherche Médicale et Sanitaire, NigerSummary. Problem. Transfusional malaria is an accidental transmission of Plasmodium via a blood transfusion. Its magnitude is underestimated and very little data on the assessment of this risk are available in Niger. Objective. This study aimed to determine the prevalence of plasmodial infection of blood bags at the National Blood Transfusion Center of Niamey (NBTC). Methodology. A cross-sectional study to diagnose Plasmodium infection by microscopy and Rapid Diagnostic Test (RDT) was carried out during the rainy season (September to November 2015). Blood grouping was performed by the BETH-VINCENT technique. Results. One thousand three hundred and fifty-seven (1357) blood bags were collected. One hundred and fifty-seven (11.6%) of the donors were infected with Plasmodium by microscopy and 2.4% (9/369) by rapid diagnostic test. All infections were with P. falciparum (100%). The mean parasite density was 197 parasites/μL (SD=281; [80: 2000]). There were no significant differences in infection prevalence between the ABO blood groups (p=0.3) or the rhesus positivity (p=08). There is also no significant difference in temporal (p=0.1) and spatial (p=0.6) distribution. Conclusion. The transmission of transfusional malaria during the rainy season is a fact in Niger. Such risks were independent of the ABO blood type and positivity for the rhesus antigen. Pretransfusion diagnosis or posttransfusion therapy should be instituted to prevent it.http://dx.doi.org/10.1155/2019/7290852 |
| spellingShingle | Aminata Iro Moustapha Mahamane Lamine Ramatoulaye Hamidou Lazoumar Ibrahim Alkassoum Daou Maman Harouna Amadou Mahaman Laouali Mahamadou Doutchi Seydou Maiguizo Ibrahim Maman Laminou Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger Journal of Tropical Medicine |
| title | Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger |
| title_full | Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger |
| title_fullStr | Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger |
| title_full_unstemmed | Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger |
| title_short | Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger |
| title_sort | transfusional malaria and associated factors at the national blood transfusion center of niamey niger |
| url | http://dx.doi.org/10.1155/2019/7290852 |
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