Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan
Tick-borne pathogens (TBPs) are a global public health issue. However, there have been few reports on the prevalence of piroplasms, Anaplasma, and Ehrlichia in Kazakhstan. To understand the distribution of piroplasms, Anaplasma, and Ehrlichia pathogens carried by ticks in Kazakhstan, a total of 10,4...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2025.1533589/full |
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| author | Weixin Zeng Zhumanov Kairat Madina Awulibieer Sansyzbay Abylay Khizat Serik Meihua Yang Yuanzhi Wang Wurelihazi Hazihan |
| author_facet | Weixin Zeng Zhumanov Kairat Madina Awulibieer Sansyzbay Abylay Khizat Serik Meihua Yang Yuanzhi Wang Wurelihazi Hazihan |
| author_sort | Weixin Zeng |
| collection | DOAJ |
| description | Tick-borne pathogens (TBPs) are a global public health issue. However, there have been few reports on the prevalence of piroplasms, Anaplasma, and Ehrlichia in Kazakhstan. To understand the distribution of piroplasms, Anaplasma, and Ehrlichia pathogens carried by ticks in Kazakhstan, a total of 10,461 ticks were collected from natural hosts (e.g., cattle, sheep, and horses) in six oblasts in eastern, southern, and western Kazakhstan between 2022 and 2024. After morphological identification, 272 representative ticks were further used for species-level detection and partial genotyping analysis of TBPs. Two Babesia species (Babesia occultans and Babesia caballi), four Theileria species (Theileria orientalis, Theileria equi, Theileria annulata, and Theileria ovis), two Anaplasma species (Anaplasma phagocytophilum and Anaplasma ovis), and three Ehrlichia species were detected. Furthermore, genotype B of B. caballi, genotype 1 (Chitose) of T. orientalis, and genotype A of T. equi were confirmed. For the first time, A. phagocytophilum, three phylogeny-independent Ehrlichia spp., genotype B of B. caballi, and genotype A of T. equi were found in Kazakhstan. These findings expand our understanding of the geographical distribution of piroplasms, Anaplasma, and Ehrlichia in Central Asia. |
| format | Article |
| id | doaj-art-030aee755b87451a8eed275b9d508ca8 |
| institution | Kabale University |
| issn | 2297-1769 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj-art-030aee755b87451a8eed275b9d508ca82025-02-03T15:05:10ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-02-011210.3389/fvets.2025.15335891533589Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in KazakhstanWeixin Zeng0Zhumanov Kairat1Madina Awulibieer2Sansyzbay Abylay3Khizat Serik4Meihua Yang5Yuanzhi Wang6Wurelihazi Hazihan7College of Animal Science and Technology, Shihezi University, Shihezi, ChinaCollege of Animal Science and Technology, Shihezi University, Shihezi, ChinaCollege of Animal Science and Technology, Shihezi University, Shihezi, ChinaKazakh National Agrarian Research University, Almaty, KazakhstanKazakh National Agrarian Research University, Almaty, KazakhstanDepartment of Forest, College of Agriculture, Shihezi University, Shihezi, ChinaNHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, School of Medicine, Shihezi University, Shihezi, ChinaCollege of Animal Science and Technology, Shihezi University, Shihezi, ChinaTick-borne pathogens (TBPs) are a global public health issue. However, there have been few reports on the prevalence of piroplasms, Anaplasma, and Ehrlichia in Kazakhstan. To understand the distribution of piroplasms, Anaplasma, and Ehrlichia pathogens carried by ticks in Kazakhstan, a total of 10,461 ticks were collected from natural hosts (e.g., cattle, sheep, and horses) in six oblasts in eastern, southern, and western Kazakhstan between 2022 and 2024. After morphological identification, 272 representative ticks were further used for species-level detection and partial genotyping analysis of TBPs. Two Babesia species (Babesia occultans and Babesia caballi), four Theileria species (Theileria orientalis, Theileria equi, Theileria annulata, and Theileria ovis), two Anaplasma species (Anaplasma phagocytophilum and Anaplasma ovis), and three Ehrlichia species were detected. Furthermore, genotype B of B. caballi, genotype 1 (Chitose) of T. orientalis, and genotype A of T. equi were confirmed. For the first time, A. phagocytophilum, three phylogeny-independent Ehrlichia spp., genotype B of B. caballi, and genotype A of T. equi were found in Kazakhstan. These findings expand our understanding of the geographical distribution of piroplasms, Anaplasma, and Ehrlichia in Central Asia.https://www.frontiersin.org/articles/10.3389/fvets.2025.1533589/fulltickstick-borne pathogensmorphological identificationgenotypeKazakhstan |
| spellingShingle | Weixin Zeng Zhumanov Kairat Madina Awulibieer Sansyzbay Abylay Khizat Serik Meihua Yang Yuanzhi Wang Wurelihazi Hazihan Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan Frontiers in Veterinary Science ticks tick-borne pathogens morphological identification genotype Kazakhstan |
| title | Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan |
| title_full | Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan |
| title_fullStr | Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan |
| title_full_unstemmed | Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan |
| title_short | Molecular detection of piroplasms, Anaplasma, and Ehrlichia species in Kazakhstan |
| title_sort | molecular detection of piroplasms anaplasma and ehrlichia species in kazakhstan |
| topic | ticks tick-borne pathogens morphological identification genotype Kazakhstan |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2025.1533589/full |
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