Comparison of Two Synthesis Methods for 3D PLA-Ibuprofen Nanofibrillar Scaffolds

Comparison of Two Synthesis Methods for 3D PLA-Ibuprofen Nanofibrillar Scaffolds

Objectives: This study aimed to synthesize polylactic acid (PLA) nanofibrillar scaffolds loaded with ibuprofen (IBU) using electrospinning (ES) and air-jet spinning (AJS). The scaffolds were evaluated for their physicochemical properties, drug release profiles, and biocompatibility to assess their p...

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Main Authors: Esteban Mena-Porras, Annaby Contreras-Aleman, María Francinie Guevara-Hidalgo, Esteban Avendaño Soto, Diego Batista Menezes, Marco Antonio Alvarez-Perez, Daniel Chavarría-Bolaños
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
drug delivery system
ibuprofen
polylactic acid
scaffold
controlled release
Online Access:https://www.mdpi.com/1999-4923/17/1/106
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