Pharmacokinetic and pharmacodynamic integration and resistance analysis of cefquinome against Streptococcus uberis in vitro dynamic model

Pharmacokinetic and pharmacodynamic integration and resistance analysis of cefquinome against Streptococcus uberis in vitro dynamic model

IntroductionStreptococcus uberis (S. uberis) is a major pathogen that causes acute clinical mastitis and its recurrent episodes in dairy cows.MethodsIn this study, a peristaltic pump one-compartment open model was established to investigate the relationship between the pharmacokinetic and pharmacody...

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Bibliographic Details
Main Authors: Chongyang Li, Junli Wang, Fanxi Guo, Fengyichi Zhang, Baochang Chen, Zihan Wang, Di Cao, Zugong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
pharmacokinetic
pharmacodynamic
simulation
dynamic model
single high dosage
multiple low-dosage
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1533892/full
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