Doublet decoding of tRNASer3 demonstrates plasticity of ribosomal decoding center
Abstract Frameshifts can be caused by specific combinations of tRNA and mRNA. The wildtype AGC-decoding E. coli tRNASer3 GCU has been shown to induce −1 ribosomal frameshifting on GCA alanine codons, and proposed to read a two-base codon instead of a canonical triplet. However, it has remained uncle...
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| Main Authors: | Shruthi Krishnaswamy, Shirin Akbar, Daniel S. D. Larsson, Yang Chen, Maria Selmer |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61016-5 |
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