Monkeypox: A comprehensive review of virology, epidemiology, and global health implications
Background: Monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV) belongs to the genus Orthopoxvirus within the Poxviridae family. MPXV is a large, enveloped, double-stranded DNA virus with a complex structure typical of poxviruses .It is closely related to variola virus (the causative...
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| Language: | English |
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Zagazig University, Faculty of Medicine
2025-08-01
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| Series: | Microbes and Infectious Diseases |
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| Online Access: | https://mid.journals.ekb.eg/article_382479_3a826adecd71be8aa0750c543a79b1c1.pdf |
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| author | Sheetal Goenka |
| author_facet | Sheetal Goenka |
| author_sort | Sheetal Goenka |
| collection | DOAJ |
| description | Background: Monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV) belongs to the genus Orthopoxvirus within the Poxviridae family. MPXV is a large, enveloped, double-stranded DNA virus with a complex structure typical of poxviruses .It is closely related to variola virus (the causative agent of smallpox), vaccinia virus, and cowpox virus, has emerged as a significant global health concern in recent years. This review provides a comprehensive analysis of MPXV, including its virology, epidemiology, clinical manifestations, diagnostic approaches, treatment options, and prevention strategies. Special emphasis is placed on the current global scenario, highlighting the unprecedented spread of monkeypox beyond its traditional endemic regions. Recent outbreaks have challenged our understanding of MPXV transmission dynamics and underscored the need for enhanced surveillance, rapid diagnostic capabilities, and effective public health interventions. This review article synthesizes the latest research findings and expert opinions to provide an up-to-date perspective on monkeypox, aiming to inform healthcare professionals, researchers, and policymakers in addressing this evolving public health challenge. |
| format | Article |
| id | doaj-art-02dfa1cafe9b4ea585cd7b9ad67c6dbd |
| institution | Kabale University |
| issn | 2682-4132 2682-4140 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Zagazig University, Faculty of Medicine |
| record_format | Article |
| series | Microbes and Infectious Diseases |
| spelling | doaj-art-02dfa1cafe9b4ea585cd7b9ad67c6dbd2025-08-20T03:59:16ZengZagazig University, Faculty of MedicineMicrobes and Infectious Diseases2682-41322682-41402025-08-016396797110.21608/mid.2024.317587.2187382479Monkeypox: A comprehensive review of virology, epidemiology, and global health implicationsSheetal Goenka0Govind Ballabh Pant Institute Of Post Graduate Medical Education And Research, Delhi, IndiaBackground: Monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV) belongs to the genus Orthopoxvirus within the Poxviridae family. MPXV is a large, enveloped, double-stranded DNA virus with a complex structure typical of poxviruses .It is closely related to variola virus (the causative agent of smallpox), vaccinia virus, and cowpox virus, has emerged as a significant global health concern in recent years. This review provides a comprehensive analysis of MPXV, including its virology, epidemiology, clinical manifestations, diagnostic approaches, treatment options, and prevention strategies. Special emphasis is placed on the current global scenario, highlighting the unprecedented spread of monkeypox beyond its traditional endemic regions. Recent outbreaks have challenged our understanding of MPXV transmission dynamics and underscored the need for enhanced surveillance, rapid diagnostic capabilities, and effective public health interventions. This review article synthesizes the latest research findings and expert opinions to provide an up-to-date perspective on monkeypox, aiming to inform healthcare professionals, researchers, and policymakers in addressing this evolving public health challenge.https://mid.journals.ekb.eg/article_382479_3a826adecd71be8aa0750c543a79b1c1.pdfmonkeypoxviruszoonotic disease |
| spellingShingle | Sheetal Goenka Monkeypox: A comprehensive review of virology, epidemiology, and global health implications Microbes and Infectious Diseases monkeypox virus zoonotic disease |
| title | Monkeypox: A comprehensive review of virology, epidemiology, and global health implications |
| title_full | Monkeypox: A comprehensive review of virology, epidemiology, and global health implications |
| title_fullStr | Monkeypox: A comprehensive review of virology, epidemiology, and global health implications |
| title_full_unstemmed | Monkeypox: A comprehensive review of virology, epidemiology, and global health implications |
| title_short | Monkeypox: A comprehensive review of virology, epidemiology, and global health implications |
| title_sort | monkeypox a comprehensive review of virology epidemiology and global health implications |
| topic | monkeypox virus zoonotic disease |
| url | https://mid.journals.ekb.eg/article_382479_3a826adecd71be8aa0750c543a79b1c1.pdf |
| work_keys_str_mv | AT sheetalgoenka monkeypoxacomprehensivereviewofvirologyepidemiologyandglobalhealthimplications |