Synthesis, Isolation and Characterization of Process-Related Impurities in Oseltamivir Phosphate

Synthesis, Isolation and Characterization of Process-Related Impurities in Oseltamivir Phosphate

Three known impurities in oseltamivir phosphate bulk drug at level 0.1% (ranging from 0.05-0.1%) were detected by gradient reverse phase high performance liquid chromatography. These impurities were preliminarily identified by the mass number of the impurities. Different experiments were conducted a...

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Bibliographic Details
Main Authors: Yogesh Kumar Sharma, Dau Dayal Agarwal, Sudesh Bhure, Sanjay Singh Rathore, Chakravir Rawat, Rajendranath Mukharjee
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/327351
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