Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis r...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2015/808314 |
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| author | Nikolaos Mouchtouris Nohra Chalouhi Ameet Chitale Robert M. Starke Stavropoula I. Tjoumakaris Robert H. Rosenwasser Pascal M. Jabbour |
| author_facet | Nikolaos Mouchtouris Nohra Chalouhi Ameet Chitale Robert M. Starke Stavropoula I. Tjoumakaris Robert H. Rosenwasser Pascal M. Jabbour |
| author_sort | Nikolaos Mouchtouris |
| collection | DOAJ |
| description | Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics. |
| format | Article |
| id | doaj-art-02d20c45530a40bdbbfbf5eefbe224ae |
| institution | OA Journals |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-02d20c45530a40bdbbfbf5eefbe224ae2025-08-20T02:03:26ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/808314808314Management of Cerebral Cavernous Malformations: From Diagnosis to TreatmentNikolaos Mouchtouris0Nohra Chalouhi1Ameet Chitale2Robert M. Starke3Stavropoula I. Tjoumakaris4Robert H. Rosenwasser5Pascal M. Jabbour6Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurological Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USADepartment of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USACerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics.http://dx.doi.org/10.1155/2015/808314 |
| spellingShingle | Nikolaos Mouchtouris Nohra Chalouhi Ameet Chitale Robert M. Starke Stavropoula I. Tjoumakaris Robert H. Rosenwasser Pascal M. Jabbour Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment The Scientific World Journal |
| title | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
| title_full | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
| title_fullStr | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
| title_full_unstemmed | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
| title_short | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
| title_sort | management of cerebral cavernous malformations from diagnosis to treatment |
| url | http://dx.doi.org/10.1155/2015/808314 |
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