Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease.
INTRODUCTION: Coronary artery disease (CAD) is one of the most common cardiovascular problems and a frequent cause of death worldwide. Multi-vessel CAD is an advanced condition in which the lumen of ≥ 3 epicardial arteries becomes narrowed due to atherosclerosis. The red blood cell distribution widt...
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Via Medica
2025-12-01
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| Series: | Folia Cardiologica |
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| Online Access: | https://journals.viamedica.pl/folia_cardiologica/article/view/103206 |
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| author | Monika Chudzicka Jarosław Drożdż |
| author_facet | Monika Chudzicka Jarosław Drożdż |
| author_sort | Monika Chudzicka |
| collection | DOAJ |
| description | INTRODUCTION: Coronary artery disease (CAD) is one of the most common cardiovascular problems and a frequent cause of death worldwide. Multi-vessel CAD is an advanced condition in which the lumen of ≥ 3 epicardial arteries becomes narrowed due to atherosclerosis. The red blood cell distribution width (RDW) is a simple parameter of blood count, expressing the anisocytosis of erythrocytes. Higher value of RDW may be related with adverse outcomes in patients with cardiovascular diseases. We examined the association between RDW and the risk of all-cause mortality and adverse cardiovascular outcomes in patients with multi-vessel CAD. MATERIAL AND METHODS: The study was performed on 112 patients with multi-vessel CAD hospitalized in the Cardiology Department of the Central Clinical Hospital of the Medical University in Lodz. Demographic and clinical characteristics were obtained, and 12-month follow-up was performed. RESULTS: Seventy-five per cent of patients with multi-vessel CAD were men. The average age was 68.2 years, and the average BMI was 29.3 kg/m². The most common comorbidities were hypercholesterolemia (94%), hypertension (91%), smoking (71%), and diabetes (45%). Most patients presented severe symptoms of angina pectoris in CCS class III (60%) and class IV (10%). The mean RDW was 13.5% (12.8–14.6). In patients with multi-vessel CAD, there was no correlation between RDW and CCS class (R = 0.05, p = 0.6296), left ventricular ejection fraction (R = 0.03, p= 0.7457), death rate in one-year follow-up (p = 0.1438), and myocardial infarction (p = 0.6592). Patients who experienced acute or decompensated heart failure (HF) had higher RDW (p = 0.0420). CONCLUSIONS: Contrary to the data available in the literature regarding patients with stable CAD, in the group of patients with multi-vessel CAD, no impact of RDW on mortality or myocardial infarction was observed. However, in the analysis, higher RDW was demonstrated to be an independent predictor for a new onset of HF or chronic HF decompensation in patients with multi-vessel CAD. |
| format | Article |
| id | doaj-art-02d0d2ed4df34889b59834c19cccb8ea |
| institution | Kabale University |
| issn | 2353-7752 2353-7760 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Via Medica |
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| series | Folia Cardiologica |
| spelling | doaj-art-02d0d2ed4df34889b59834c19cccb8ea2025-08-21T07:13:49ZengVia MedicaFolia Cardiologica2353-77522353-77602025-12-0120110.5603/fc.103206Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease.Monika Chudzicka0Jarosław Drożdż12nd Department of Cardiology, Central Clinical Hospital, Medical University of Lodz, Pomorska 251, 92-213 Łódź, Polska2nd Department of Cardiology, Central Clinical Hospital, Medical University of Lodz, Pomorska 251, 92-213 Łódź, PolskaINTRODUCTION: Coronary artery disease (CAD) is one of the most common cardiovascular problems and a frequent cause of death worldwide. Multi-vessel CAD is an advanced condition in which the lumen of ≥ 3 epicardial arteries becomes narrowed due to atherosclerosis. The red blood cell distribution width (RDW) is a simple parameter of blood count, expressing the anisocytosis of erythrocytes. Higher value of RDW may be related with adverse outcomes in patients with cardiovascular diseases. We examined the association between RDW and the risk of all-cause mortality and adverse cardiovascular outcomes in patients with multi-vessel CAD. MATERIAL AND METHODS: The study was performed on 112 patients with multi-vessel CAD hospitalized in the Cardiology Department of the Central Clinical Hospital of the Medical University in Lodz. Demographic and clinical characteristics were obtained, and 12-month follow-up was performed. RESULTS: Seventy-five per cent of patients with multi-vessel CAD were men. The average age was 68.2 years, and the average BMI was 29.3 kg/m². The most common comorbidities were hypercholesterolemia (94%), hypertension (91%), smoking (71%), and diabetes (45%). Most patients presented severe symptoms of angina pectoris in CCS class III (60%) and class IV (10%). The mean RDW was 13.5% (12.8–14.6). In patients with multi-vessel CAD, there was no correlation between RDW and CCS class (R = 0.05, p = 0.6296), left ventricular ejection fraction (R = 0.03, p= 0.7457), death rate in one-year follow-up (p = 0.1438), and myocardial infarction (p = 0.6592). Patients who experienced acute or decompensated heart failure (HF) had higher RDW (p = 0.0420). CONCLUSIONS: Contrary to the data available in the literature regarding patients with stable CAD, in the group of patients with multi-vessel CAD, no impact of RDW on mortality or myocardial infarction was observed. However, in the analysis, higher RDW was demonstrated to be an independent predictor for a new onset of HF or chronic HF decompensation in patients with multi-vessel CAD.https://journals.viamedica.pl/folia_cardiologica/article/view/103206multivessel coronary artery diseasered blood cell distribution widthheart failurerisk factor |
| spellingShingle | Monika Chudzicka Jarosław Drożdż Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease. Folia Cardiologica multivessel coronary artery disease red blood cell distribution width heart failure risk factor |
| title | Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease. |
| title_full | Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease. |
| title_fullStr | Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease. |
| title_full_unstemmed | Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease. |
| title_short | Prognostic value of red blood cell distribution width (RDW) in patients with multi-vessel coronary artery disease. |
| title_sort | prognostic value of red blood cell distribution width rdw in patients with multi vessel coronary artery disease |
| topic | multivessel coronary artery disease red blood cell distribution width heart failure risk factor |
| url | https://journals.viamedica.pl/folia_cardiologica/article/view/103206 |
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