Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain.

Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein mu1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection. Ectopic expression of full-length and truncated...

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Bibliographic Details
Main Authors: Pranav Danthi, Caroline M Coffey, John S L Parker, Ty W Abel, Terence S Dermody
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000248&type=printable
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