Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain.
Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein mu1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection. Ectopic expression of full-length and truncated...
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| Main Authors: | Pranav Danthi, Caroline M Coffey, John S L Parker, Ty W Abel, Terence S Dermody |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-12-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000248&type=printable |
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