Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study

Aim: The aim of the study was to evaluate the pH, free available chlorine (FAC), and tissue dissolution property of various chlorine-releasing solutions prepared from predosed tablets based on the period since the preparation of the solution. Methods: Groups 1–3 are the study solutions prepared by d...

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Main Authors: S. Aishwarya, Debolina Bishayi, Vinod Rakesh Jathanna, Manuel S. Thomas, Srikant Natarajan, Suchitra Shenoy, Aradhana Marathe
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Endodontology
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Online Access:https://journals.lww.com/10.4103/endo.endo_114_24
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author S. Aishwarya
Debolina Bishayi
Vinod Rakesh Jathanna
Manuel S. Thomas
Srikant Natarajan
Suchitra Shenoy
Aradhana Marathe
author_facet S. Aishwarya
Debolina Bishayi
Vinod Rakesh Jathanna
Manuel S. Thomas
Srikant Natarajan
Suchitra Shenoy
Aradhana Marathe
author_sort S. Aishwarya
collection DOAJ
description Aim: The aim of the study was to evaluate the pH, free available chlorine (FAC), and tissue dissolution property of various chlorine-releasing solutions prepared from predosed tablets based on the period since the preparation of the solution. Methods: Groups 1–3 are the study solutions prepared by dissolving 2.5 g of the chemical in powder form in 100 mL distilled water to obtain a 2.5% solution. The control solution is the commercially available 2.5% sodium hypochlorite (NaOCl) solution. The solutions were freshly prepared and used immediately before testing each aspect of the study. (1) Group 1: 2.5% calcium hypochlorite, (2) Group 2: 2.5% chlorine dioxide (ClO2), (3) Group 3: 2.5% sodium dichloroisocyanurate, (4) Group 4: 2.5% NaOCl, (5) Group 5: saline (negative control). Results: The comparison of pH, FAC, and tissue dissolution property between NaOCl and ClO2 was statistically nonsignificant, whereas the comparison was significant with respect to the other test solutions. Conclusion: ClO2 shows more similarity to NaOCl as an irrigant used for root canal treatments. There was not any significant difference between ClO2 and NaOCl in its FAC and tissue dissolution properties.
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spelling doaj-art-02b9a154bdad424f891c097fdebbf8eb2025-08-20T03:16:10ZengWolters Kluwer Medknow PublicationsEndodontology0970-72122543-08312025-04-0137221722110.4103/endo.endo_114_24Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro studyS. AishwaryaDebolina BishayiVinod Rakesh JathannaManuel S. ThomasSrikant NatarajanSuchitra ShenoyAradhana MaratheAim: The aim of the study was to evaluate the pH, free available chlorine (FAC), and tissue dissolution property of various chlorine-releasing solutions prepared from predosed tablets based on the period since the preparation of the solution. Methods: Groups 1–3 are the study solutions prepared by dissolving 2.5 g of the chemical in powder form in 100 mL distilled water to obtain a 2.5% solution. The control solution is the commercially available 2.5% sodium hypochlorite (NaOCl) solution. The solutions were freshly prepared and used immediately before testing each aspect of the study. (1) Group 1: 2.5% calcium hypochlorite, (2) Group 2: 2.5% chlorine dioxide (ClO2), (3) Group 3: 2.5% sodium dichloroisocyanurate, (4) Group 4: 2.5% NaOCl, (5) Group 5: saline (negative control). Results: The comparison of pH, FAC, and tissue dissolution property between NaOCl and ClO2 was statistically nonsignificant, whereas the comparison was significant with respect to the other test solutions. Conclusion: ClO2 shows more similarity to NaOCl as an irrigant used for root canal treatments. There was not any significant difference between ClO2 and NaOCl in its FAC and tissue dissolution properties.https://journals.lww.com/10.4103/endo.endo_114_24calcium hypochloritechlorine dioxideroot canal irrigantsodium dichloroisocyanuratesodium hypochlorite
spellingShingle S. Aishwarya
Debolina Bishayi
Vinod Rakesh Jathanna
Manuel S. Thomas
Srikant Natarajan
Suchitra Shenoy
Aradhana Marathe
Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study
Endodontology
calcium hypochlorite
chlorine dioxide
root canal irrigant
sodium dichloroisocyanurate
sodium hypochlorite
title Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study
title_full Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study
title_fullStr Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study
title_full_unstemmed Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study
title_short Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study
title_sort evaluation of ph free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time an in vitro study
topic calcium hypochlorite
chlorine dioxide
root canal irrigant
sodium dichloroisocyanurate
sodium hypochlorite
url https://journals.lww.com/10.4103/endo.endo_114_24
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