Comparison of various methodological approaches to model asbestos thresholds for mesothelioma

Comparison of various methodological approaches to model asbestos thresholds for mesothelioma

BackgroundThere is evidence to support several modes of action (MoAs), and particularly non-genotoxic MoAs, for mesothelioma induced by asbestiform elongate mineral particles (EMPs). In turn, these MoAs provide biological support for dose-response relationships that are non-linear and that include a...

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Bibliographic Details
Main Authors: Julie E. Goodman, Andrey Korchevskiy, Ann G. Wylie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Public Health
Subjects:
threshold
mesothelioma
asbestos
chrysotile
amphibole
dose-response
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1569343/full
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