Immature forms of low density granulocytes are increased in acute myeloid leukemia and myelodysplastic syndromes

Immature forms of low density granulocytes are increased in acute myeloid leukemia and myelodysplastic syndromes

Abstract Neutrophils can promote or suppress tumor growth. These different immunological functions mirror a great heterogenicity of neutrophil maturation and activation status: low-density granulocytes (LDGs) and normal-density neutrophils (NDNs). LDGs participate in immune dysregulation during auto...

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Bibliographic Details
Main Authors: Angela Bertolini, Francesca Picone, Idalucia Ferrara, Anna Maria Della Corte, Bianca Serio, Marisa Gorrese, Annapaola Campana, Vittorio Simeon, Serena Luponio, Rossella Marcucci, Pasqualina Scala, Maddalena Langella, Carmine Selleri, Valentina Giudice
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-92513-8
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