Uniform impact on individual megakaryocytes is essential for efficient in vitro platelet production

Uniform impact on individual megakaryocytes is essential for efficient in vitro platelet production

Abstract Different approaches are being developed to efficiently produce in vitro platelets from cultured megakaryocytes to meet the constant demand of platelet transfusion and serve for research purposes. Recent works have shown that turbulence and periodic stress can significantly enhance platelet...

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Bibliographic Details
Main Authors: Andrei K. Garzon Dasgupta, Anaïs Pongérard, Léa Mallo, Anita Eckly, François Lanza, Olivier Boiron, Yannick Knapp, Catherine Strassel
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Cultured platelets
CFD
Online Access:https://doi.org/10.1038/s41598-024-79949-0
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