Effects of Sildenafil and Vitamin E on Paraquat-Induced Pulmonary Fibrosis in Rats

Effects of Sildenafil and Vitamin E on Paraquat-Induced Pulmonary Fibrosis in Rats

Paraquat, specifically concentrated in lung tissue, leads to lung damage through oxidative and inflammatory processes. Pulmonary fibrosis occurs due to inflammation and an imbalance in the antioxidant system. Drugs like sildenafil, which inhibits phosphodiesterase enzymes, are used to treat pulmonar...

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Bibliographic Details
Main Authors: Fouziyeh Siahpour, Hosein Sadeghi, Esmaeel Panahi kokhdan, Mohammad Khoshnoud
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2024-12-01
Series:Trends in Pharmaceutical Sciences
Subjects:
paraquat
sildenafil
vitamin e
pulmonary fibrosis
Online Access:https://tips.sums.ac.ir/article_50536_617ff9bd34fc087abfdefb2135e03804.pdf
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