Protective effects of naringin against oxidative stress, inflammation, apoptosis, and DNA damage in rats with doxorubicin-induced hepatotoxicity

Protective effects of naringin against oxidative stress, inflammation, apoptosis, and DNA damage in rats with doxorubicin-induced hepatotoxicity

Objective: To investigate the protective effects of naringin on doxorubicin (DOX)-induced liver injury. Methods: A total of 50 male rats were allocated into five groups: the control group, the DOX group, the DOX groups treated with 50 mg/kg and 100 mg/kg of naringin by gastric lavage for 10 days, as...

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Bibliographic Details
Main Authors: Pelin Durukan Azman, Serkan Yildirim, Emin Sengul, Mohamad Warda, Samet Tekin, Furkan Aykurt, Ali Cinar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
doxorubicin
hepatotoxicity
inflammation
naringin
oxidative stress
Online Access:https://journals.lww.com/10.4103/apjtb.apjtb_139_25
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