AKR1C3 protects cardiomyocytes against hypoxia-induced cell apoptosis through the Nrf-2/NF-κB pathway

AKR1C3 protects cardiomyocytes against hypoxia-induced cell apoptosis through the Nrf-2/NF-κB pathway

Hypoxia-induced apoptosis plays a critical role in the progression of various cardiac diseases, such as heart failure and acute myocardial infarction (AMI). Aldosterone reductase 1C3 (AKR1C3), a member of the aldo-keto reductase superfamily, participates in the metabolism of steroid hormones and red...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang Wenlu, Tian Wei, Xia Xin, Tian Hua, Sun Ting
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
AKR1C3
hypoxia
cardiomyocyte apoptosis
Nrf-2
NF-κB
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024230
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items