Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023
Abstract Background Feline blood transfusion is required for the treatment of various illnesses in cats, and the safety of donor cats is vital. Donor adverse reactions can include cardiorespiratory, venepuncture‐related, and behavioral abnormalities. Hypothesis/Objectives To describe a large number...
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| Format: | Article |
| Language: | English |
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Wiley
2024-11-01
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| Series: | Journal of Veterinary Internal Medicine |
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| Online Access: | https://doi.org/10.1111/jvim.17215 |
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| author | Samantha S. Taylor Helena C.M. Ferreira André F.P. Cambra Giovanni Lo Iacono Kamalan Jeevaratnam Ignacio Mesa‐Sanchez Rui R.F. Ferreira |
| author_facet | Samantha S. Taylor Helena C.M. Ferreira André F.P. Cambra Giovanni Lo Iacono Kamalan Jeevaratnam Ignacio Mesa‐Sanchez Rui R.F. Ferreira |
| author_sort | Samantha S. Taylor |
| collection | DOAJ |
| description | Abstract Background Feline blood transfusion is required for the treatment of various illnesses in cats, and the safety of donor cats is vital. Donor adverse reactions can include cardiorespiratory, venepuncture‐related, and behavioral abnormalities. Hypothesis/Objectives To describe a large number of feline blood donation events and document use of sedation and anxiolysis, record volume of blood collected and describe the frequency, type, and risk factors for, adverse reactions. Animals The study included 7812 individual cats and 29 201 donation events at a blood banking center over 5 years. Methods Retrospective analysis of donation event records with signalment, donation volume, sedation status, donation number, and adverse reactions (acute and caregiver reported) recorded. Risk factors for adverse reactions were examined by stratifying data according to groups exposed to relevant predictors and calculating odds ratios with 95% and 99% confidence intervals (CIs). Results Adverse reactions were uncommon (0.29%, 2.88/1000 donor events) and most commonly were cardiorespiratory (0.08%, 0.75/1000 donor events) or behavioral (0.06%, 0.62/1000 donor events). The only risk factor significantly associated with adverse reactions was conscious donation, with conscious donors 4.4 times more likely to have an adverse reaction (95% CI, 2.5‐7.9, P ≤ .0001). Conclusions and Clinical Importance Feline blood donation is associated with a low rate of adverse reactions. Sedation should be considered to reduce adverse reactions, and the environment and interactions optimized to reduce donor stress. Caregiver education on care postdonation could reduce behavioral adverse reactions. |
| format | Article |
| id | doaj-art-02895811683f4a018c3dd2a279a8c3ca |
| institution | OA Journals |
| issn | 0891-6640 1939-1676 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj-art-02895811683f4a018c3dd2a279a8c3ca2025-08-20T02:23:40ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762024-11-013863050306210.1111/jvim.17215Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023Samantha S. Taylor0Helena C.M. Ferreira1André F.P. Cambra2Giovanni Lo Iacono3Kamalan Jeevaratnam4Ignacio Mesa‐Sanchez5Rui R.F. Ferreira6School of Veterinary Medicine University of Surrey Guildford United KingdomAnimal Blood Bank Porto PortugalAnimal Blood Bank Porto PortugalSchool of Veterinary Medicine University of Surrey Guildford United KingdomSchool of Veterinary Medicine University of Surrey Guildford United KingdomAnimal Blood Bank Porto PortugalAnimal Blood Bank Porto PortugalAbstract Background Feline blood transfusion is required for the treatment of various illnesses in cats, and the safety of donor cats is vital. Donor adverse reactions can include cardiorespiratory, venepuncture‐related, and behavioral abnormalities. Hypothesis/Objectives To describe a large number of feline blood donation events and document use of sedation and anxiolysis, record volume of blood collected and describe the frequency, type, and risk factors for, adverse reactions. Animals The study included 7812 individual cats and 29 201 donation events at a blood banking center over 5 years. Methods Retrospective analysis of donation event records with signalment, donation volume, sedation status, donation number, and adverse reactions (acute and caregiver reported) recorded. Risk factors for adverse reactions were examined by stratifying data according to groups exposed to relevant predictors and calculating odds ratios with 95% and 99% confidence intervals (CIs). Results Adverse reactions were uncommon (0.29%, 2.88/1000 donor events) and most commonly were cardiorespiratory (0.08%, 0.75/1000 donor events) or behavioral (0.06%, 0.62/1000 donor events). The only risk factor significantly associated with adverse reactions was conscious donation, with conscious donors 4.4 times more likely to have an adverse reaction (95% CI, 2.5‐7.9, P ≤ .0001). Conclusions and Clinical Importance Feline blood donation is associated with a low rate of adverse reactions. Sedation should be considered to reduce adverse reactions, and the environment and interactions optimized to reduce donor stress. Caregiver education on care postdonation could reduce behavioral adverse reactions.https://doi.org/10.1111/jvim.17215anxiolysisblood collectionblood donationblood groupblood transfusioncat |
| spellingShingle | Samantha S. Taylor Helena C.M. Ferreira André F.P. Cambra Giovanni Lo Iacono Kamalan Jeevaratnam Ignacio Mesa‐Sanchez Rui R.F. Ferreira Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023 Journal of Veterinary Internal Medicine anxiolysis blood collection blood donation blood group blood transfusion cat |
| title | Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023 |
| title_full | Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023 |
| title_fullStr | Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023 |
| title_full_unstemmed | Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023 |
| title_short | Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023 |
| title_sort | feline blood donation description and adverse reactions from 29 201 donation events between 2019 and 2023 |
| topic | anxiolysis blood collection blood donation blood group blood transfusion cat |
| url | https://doi.org/10.1111/jvim.17215 |
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