TET1: The epigenetic architect of clinical disease progression
The ten-eleven translocation 1 (TET1) protein, a member of the human α-ketoglutarate-dependent dioxygenase TET family, functions as a 5-methylcytosine hydroxylase with a strong affinity for genomic regions enriched with 5′-CpG-3′ dinucleotides, particularly CpG islands. TET1 is critical in initiatin...
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| Main Authors: | Keyvan Jabbari, Ali Khalafizadeh, Mahboubeh Sheikhbahaei, Hossein Soltaninejad, Sadegh Babashah |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2025-09-01
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| Series: | Genes and Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304225000029 |
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