S–6P exhibits better immunogenicity than S–2P at lower doses of COVID-19 mRNA vaccines

Objective: The objective of this study was to determine whether a new combination of immunogens could be more effective than the S–2P design in terms of eliciting an immune response. The study aimed to use a unified formulation standard to make a comparison between the new immunogen combination than...

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Bibliographic Details
Main Authors:	Zhongyi Zhu, Lei Zhang, Shuangbao Li, Yang Gao, Yuwei Wang, Xiaofei Ma, Zhonglin Chen, Siyu Wu, Yonghui Zhang, Mengyuan Zhang, Zhihao Xie, Changcheng Yin, Weijun Chen, Fuxing Zeng, Jinmin Ma
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2024-01-01
Series:	Decoding Infection and Transmission
Subjects:	SARS-COV-2 mRNA vaccines S-2P S-6P Spike protein Furin cleavage site
Online Access:	http://www.sciencedirect.com/science/article/pii/S2949924024000016
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S–6P exhibits better immunogenicity than S–2P at lower doses of COVID-19 mRNA vaccines

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