Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management
Oesophageal adenocarcinoma (EAC) is increasingly associated with obesity, metabolic dysfunction, and genetic predispositions. This review explores how nutritional factors interact with these risk elements, emphasizing the potential of dietary strategies in EAC prevention and management. Diets such a...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Food and Agricultural Immunology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/09540105.2025.2510951 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850123323806056448 |
|---|---|
| author | Claudia Reytor-González Daniel Simancas-Racines Emilia Jiménez-Flores Martín Campuzano-Donoso Angelo Michele Carella Luigi Coppola Marco Marchetti Raynier Zambrano-Villacres Gerardo Sarno |
| author_facet | Claudia Reytor-González Daniel Simancas-Racines Emilia Jiménez-Flores Martín Campuzano-Donoso Angelo Michele Carella Luigi Coppola Marco Marchetti Raynier Zambrano-Villacres Gerardo Sarno |
| author_sort | Claudia Reytor-González |
| collection | DOAJ |
| description | Oesophageal adenocarcinoma (EAC) is increasingly associated with obesity, metabolic dysfunction, and genetic predispositions. This review explores how nutritional factors interact with these risk elements, emphasizing the potential of dietary strategies in EAC prevention and management. Diets such as the Mediterranean and plant-based patterns may reduce inflammation, oxidative stress, and metabolic imbalance, thereby modulating cancer risk. Nutrient-rich foods – particularly omega-3 fatty acids, cruciferous vegetables, and dietary fibre – offer additional protective effects. Personalized nutrition, tailored to individual genetic and metabolic profiles, is emerging as a promising tool in cancer prevention. Moreover, weight management strategies like caloric restriction and intermittent fasting may contribute to risk reduction. Integrating these approaches into clinical and public health practices could play a critical role in mitigating the underlying drivers of EAC. Further research is needed to strengthen dietary guidelines and advance precision nutrition for high-risk populations. |
| format | Article |
| id | doaj-art-027f94f062124e11abb9e3a820e505fe |
| institution | OA Journals |
| issn | 0954-0105 1465-3443 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Food and Agricultural Immunology |
| spelling | doaj-art-027f94f062124e11abb9e3a820e505fe2025-08-20T02:34:36ZengTaylor & Francis GroupFood and Agricultural Immunology0954-01051465-34432025-12-0136110.1080/09540105.2025.2510951Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and managementClaudia Reytor-González0Daniel Simancas-Racines1Emilia Jiménez-Flores2Martín Campuzano-Donoso3Angelo Michele Carella4Luigi Coppola5Marco Marchetti6Raynier Zambrano-Villacres7Gerardo Sarno8Facultad de Ciencias de la Salud Eugenio Espejo, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Universidad UTE, Quito, EcuadorFacultad de Ciencias de la Salud Eugenio Espejo, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Universidad UTE, Quito, EcuadorFacultad de Ciencias de la Salud Eugenio Espejo, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Universidad UTE, Quito, EcuadorFacultad de Ciencias de la Salud Eugenio Espejo, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Universidad UTE, Quito, EcuadorInternal Medicine Department, “T. Masselli-Mascia” Hospital-San Severo (Foggia), Foggia, ItalyUniversity of Sannio, Benevento, ItalyDepartmental Faculty of Medicine, UniCamillus-Saint Camillus International University of Health Sciences, Rome, ItalyEscuela de Nutrición y Dietética, Universidad Espíritu Santo, Samborondón, Ecuador“San Giovanni di Dio e Ruggi D’Aragona” University Hospital, Salerno, ItalyOesophageal adenocarcinoma (EAC) is increasingly associated with obesity, metabolic dysfunction, and genetic predispositions. This review explores how nutritional factors interact with these risk elements, emphasizing the potential of dietary strategies in EAC prevention and management. Diets such as the Mediterranean and plant-based patterns may reduce inflammation, oxidative stress, and metabolic imbalance, thereby modulating cancer risk. Nutrient-rich foods – particularly omega-3 fatty acids, cruciferous vegetables, and dietary fibre – offer additional protective effects. Personalized nutrition, tailored to individual genetic and metabolic profiles, is emerging as a promising tool in cancer prevention. Moreover, weight management strategies like caloric restriction and intermittent fasting may contribute to risk reduction. Integrating these approaches into clinical and public health practices could play a critical role in mitigating the underlying drivers of EAC. Further research is needed to strengthen dietary guidelines and advance precision nutrition for high-risk populations.https://www.tandfonline.com/doi/10.1080/09540105.2025.2510951Oesophageal adenocarcinomacancerobesitynutritionnutritional strategieshealthcare |
| spellingShingle | Claudia Reytor-González Daniel Simancas-Racines Emilia Jiménez-Flores Martín Campuzano-Donoso Angelo Michele Carella Luigi Coppola Marco Marchetti Raynier Zambrano-Villacres Gerardo Sarno Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management Food and Agricultural Immunology Oesophageal adenocarcinoma cancer obesity nutrition nutritional strategies healthcare |
| title | Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management |
| title_full | Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management |
| title_fullStr | Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management |
| title_full_unstemmed | Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management |
| title_short | Oesophageal adenocarcinoma, obesity, and cancer: the role of nutrition in prevention and management |
| title_sort | oesophageal adenocarcinoma obesity and cancer the role of nutrition in prevention and management |
| topic | Oesophageal adenocarcinoma cancer obesity nutrition nutritional strategies healthcare |
| url | https://www.tandfonline.com/doi/10.1080/09540105.2025.2510951 |
| work_keys_str_mv | AT claudiareytorgonzalez oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT danielsimancasracines oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT emiliajimenezflores oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT martincampuzanodonoso oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT angelomichelecarella oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT luigicoppola oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT marcomarchetti oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT raynierzambranovillacres oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement AT gerardosarno oesophagealadenocarcinomaobesityandcancertheroleofnutritioninpreventionandmanagement |