Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion

Aim. To determine the reproducibility of the results of instantaneous wavefree ratio (iFR) and angiography coregistration in patients with coronary heart disease (CAD) with multilevel and diffuse lesions of the coronary arteries.Materials and methods. The study included 34 patients with chronic isch...

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Main Authors: D. S. Bubnov, R. V. Atanesyan, Z. B. Kardanakhishvili, F. T. Ageev, Yu. G. Matchin
Format: Article
Language:Russian
Published: InterMedservice 2023-11-01
Series:Евразийский Кардиологический Журнал
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Online Access:https://www.heartj.asia/jour/article/view/6424
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author D. S. Bubnov
R. V. Atanesyan
Z. B. Kardanakhishvili
F. T. Ageev
Yu. G. Matchin
author_facet D. S. Bubnov
R. V. Atanesyan
Z. B. Kardanakhishvili
F. T. Ageev
Yu. G. Matchin
author_sort D. S. Bubnov
collection DOAJ
description Aim. To determine the reproducibility of the results of instantaneous wavefree ratio (iFR) and angiography coregistration in patients with coronary heart disease (CAD) with multilevel and diffuse lesions of the coronary arteries.Materials and methods. The study included 34 patients with chronic ischemic heart disease (CAD) with diffuse and/or multilevel coronary stenoses >50%. In 41 coronary arteries, two consecutive iFR pullback of the conductor were performed and paired iFR angio-coregistrations were formed, reflecting changes in iFR gradients (Δ iFR) along the entire length of the studied artery. To compare the results of paired studies, the following values were used: 1) indices of distal iFR; 2) maximum Δ iFR; 3) Δ iFR of all stenoses ˃50%.Results. Comparable values of distal iFR were obtained 0,84 [0,78; 0,89] vs. 0,85 [0,77; 0,88]) with an average difference of the first and second measurements of 0,001, maximum ΔiFR (0,08 [0,05; 0,14] vs. 0,08 [0,05; 0,13]) with a mean difference of -0,004 and ΔiFR of all stenoses >50% (0,05 [0,02; 0,11] vs. 0,05 [ 0,02; 0,10]) with an average difference of -0.001. Lin’s concordance correlation coefficient and Intraclass Correlation Coefficients calculated for the three parameters studied showed a good level of agreement (0,97; 0,98; 0,98) with excellent reliability (0,97; 0,98; 0,97).Conclusion. In patients with multilevel and diffuse lesions of the coronary artery, iFR angio-coregistration has a fairly high reproducibility.
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spelling doaj-art-0277cbb03a06431a95f4e119772b03cd2025-08-20T03:58:59ZrusInterMedserviceЕвразийский Кардиологический Журнал2225-16852305-07482023-11-0104324010.38109/2225-1685-2023-4-32-406321Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesionD. S. Bubnov0R. V. Atanesyan1Z. B. Kardanakhishvili2F. T. Ageev3Yu. G. Matchin4E.I. Chazov National Medical Research Center of CardiologyE.I. Chazov National Medical Research Center of CardiologyE.I. Chazov National Medical Research Center of CardiologyE.I. Chazov National Medical Research Center of CardiologyE.I. Chazov National Medical Research Center of CardiologyAim. To determine the reproducibility of the results of instantaneous wavefree ratio (iFR) and angiography coregistration in patients with coronary heart disease (CAD) with multilevel and diffuse lesions of the coronary arteries.Materials and methods. The study included 34 patients with chronic ischemic heart disease (CAD) with diffuse and/or multilevel coronary stenoses >50%. In 41 coronary arteries, two consecutive iFR pullback of the conductor were performed and paired iFR angio-coregistrations were formed, reflecting changes in iFR gradients (Δ iFR) along the entire length of the studied artery. To compare the results of paired studies, the following values were used: 1) indices of distal iFR; 2) maximum Δ iFR; 3) Δ iFR of all stenoses ˃50%.Results. Comparable values of distal iFR were obtained 0,84 [0,78; 0,89] vs. 0,85 [0,77; 0,88]) with an average difference of the first and second measurements of 0,001, maximum ΔiFR (0,08 [0,05; 0,14] vs. 0,08 [0,05; 0,13]) with a mean difference of -0,004 and ΔiFR of all stenoses >50% (0,05 [0,02; 0,11] vs. 0,05 [ 0,02; 0,10]) with an average difference of -0.001. Lin’s concordance correlation coefficient and Intraclass Correlation Coefficients calculated for the three parameters studied showed a good level of agreement (0,97; 0,98; 0,98) with excellent reliability (0,97; 0,98; 0,97).Conclusion. In patients with multilevel and diffuse lesions of the coronary artery, iFR angio-coregistration has a fairly high reproducibility.https://www.heartj.asia/jour/article/view/6424coronary artery diseasediffuse coronary artery lesionmultilevel coronary artery lesionifr pressure-wire pullbackifr angio-coregistrationreproducibility
spellingShingle D. S. Bubnov
R. V. Atanesyan
Z. B. Kardanakhishvili
F. T. Ageev
Yu. G. Matchin
Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
Евразийский Кардиологический Журнал
coronary artery disease
diffuse coronary artery lesion
multilevel coronary artery lesion
ifr pressure-wire pullback
ifr angio-coregistration
reproducibility
title Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
title_full Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
title_fullStr Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
title_full_unstemmed Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
title_short Reproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
title_sort reproducibility of instantaneous wave free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesion
topic coronary artery disease
diffuse coronary artery lesion
multilevel coronary artery lesion
ifr pressure-wire pullback
ifr angio-coregistration
reproducibility
url https://www.heartj.asia/jour/article/view/6424
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AT ftageev reproducibilityofinstantaneouswavefreeratioandangiographycoregistrationinpatientswithcoronaryheartdiseaseanddiffuseandmultilevelcoronaryarterylesion
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