Interferon therapy for chronic hepatitis B virus infection affects nucleoside metabolism: a metabolomics study

Interferon therapy for chronic hepatitis B virus infection affects nucleoside metabolism: a metabolomics study

Abstract Pegylated interferon alfa (pegIFN-α) is one of the main therapeutic strategies for chronic hepatitis B (CHB) infection. Although interferon-based treatment strategies have great potential in combating CHB, they have significant side effects, and many patients do not respond. In this study,...

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Main Authors: Xiangyang Ye, Rongxian Qiu, Xiongzhi He, Zhenting Hu, Fengfeng Zheng, Xiaogang Huang, Xuemei Xie, Feihua Chen, Hanbing Ou
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Gastroenterology
Subjects:
Hepatitis B virus
Interferon treatment
Metabolomics
Methylated modification
Nucleoside metabolism
Online Access:https://doi.org/10.1186/s12876-025-04126-0
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