Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report
Abstract Objective Tricyclic antidepressants (TCAs) are used to treat depression, but if abused or misused, they can cause poisoning, which can be fatal. The main treatment for TCA poisoning is administering sodium bicarbonate. Methods We report a 16-year-old girl diagnosed with nortriptyline poison...
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| Format: | Article |
| Language: | English |
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BMC
2025-03-01
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| Series: | International Journal of Emergency Medicine |
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| Online Access: | https://doi.org/10.1186/s12245-025-00824-4 |
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| author | Asma Ahmadinejad Amir Saeed Marzieh Davoodi |
| author_facet | Asma Ahmadinejad Amir Saeed Marzieh Davoodi |
| author_sort | Asma Ahmadinejad |
| collection | DOAJ |
| description | Abstract Objective Tricyclic antidepressants (TCAs) are used to treat depression, but if abused or misused, they can cause poisoning, which can be fatal. The main treatment for TCA poisoning is administering sodium bicarbonate. Methods We report a 16-year-old girl diagnosed with nortriptyline poisoning with a profound neurologic and cardiovascular manifestations, successfully treated using sodium bicarbonate, intralipid emulsion, and plasmapheresis. Conclusions Plasmapheresis can be a good treatment modality for patients with TCA poisoning who do not respond well to classic treatments. |
| format | Article |
| id | doaj-art-02604980104243e4ac2d70ae6abc5a4e |
| institution | Kabale University |
| issn | 1865-1380 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | International Journal of Emergency Medicine |
| spelling | doaj-art-02604980104243e4ac2d70ae6abc5a4e2025-08-20T03:40:44ZengBMCInternational Journal of Emergency Medicine1865-13802025-03-011811410.1186/s12245-025-00824-4Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case reportAsma Ahmadinejad0Amir Saeed1Marzieh Davoodi2Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical SciencesDepartment of Pediatrics, Division of Pediatric Intensive Care, Shiraz University of Medical SciencesNeonatal Research Center, Department of Pediatrics, School of Medicine, Shiraz University of Medical SciencesAbstract Objective Tricyclic antidepressants (TCAs) are used to treat depression, but if abused or misused, they can cause poisoning, which can be fatal. The main treatment for TCA poisoning is administering sodium bicarbonate. Methods We report a 16-year-old girl diagnosed with nortriptyline poisoning with a profound neurologic and cardiovascular manifestations, successfully treated using sodium bicarbonate, intralipid emulsion, and plasmapheresis. Conclusions Plasmapheresis can be a good treatment modality for patients with TCA poisoning who do not respond well to classic treatments.https://doi.org/10.1186/s12245-025-00824-4TCAPlasmapheresisIntralipid |
| spellingShingle | Asma Ahmadinejad Amir Saeed Marzieh Davoodi Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report International Journal of Emergency Medicine TCA Plasmapheresis Intralipid |
| title | Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report |
| title_full | Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report |
| title_fullStr | Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report |
| title_full_unstemmed | Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report |
| title_short | Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report |
| title_sort | successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning a case report |
| topic | TCA Plasmapheresis Intralipid |
| url | https://doi.org/10.1186/s12245-025-00824-4 |
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