Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography
The aim of this study was to evaluate the diagnostic value of high-frequency ultrasonography in detecting atrophy of foot muscles in Chinese patients of type 2 diabetes mellitus (T2DM). Chinese patients of T2DM with (n=56) or without (n=50) diabetic peripheral neuropathy (DPN) and the control subjec...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2014/927069 |
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| author | Xiaohui Wang Liang Chen Weiwei Liu Benli Su Yuhong Zhang |
| author_facet | Xiaohui Wang Liang Chen Weiwei Liu Benli Su Yuhong Zhang |
| author_sort | Xiaohui Wang |
| collection | DOAJ |
| description | The aim of this study was to evaluate the diagnostic value of high-frequency ultrasonography in detecting atrophy of foot muscles in Chinese patients of type 2 diabetes mellitus (T2DM). Chinese patients of T2DM with (n=56) or without (n=50) diabetic peripheral neuropathy (DPN) and the control subjects (n=50) were enrolled. The nondominant foot of all subjects was examined with high-frequency ultrasonography. The transverse diameter, thickness, and cross-sectional area of the extensor digitorum brevis muscle (EDB) and the thickness of the muscles of the first interstitium (MILs) were measured. The results showed that the ultrasonographic transverse diameter, thickness, and cross-sectional area of EDB and the thickness of MILs in patients of T2DM with DPN were significantly smaller than those in patients of T2DM without DPN (all P<0.01) and those in the control subjects (all P<0.01). The transverse diameter and cross-sectional area of the EDB and thickness of MILs in patients of T2DM without DPN were significantly smaller than those of the control subjects (all P<0.01). In conclusion, the atrophy of foot muscle in Chinese T2DM patients can be detected by high-frequency ultrasonography. Notably, ultrasonography may detect early atrophy of foot muscles in patients without DPN. |
| format | Article |
| id | doaj-art-025e7c1da8b144d4a836c2325f789321 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-025e7c1da8b144d4a836c2325f7893212025-08-20T03:55:32ZengWileyJournal of Diabetes Research2314-67452314-67532014-01-01201410.1155/2014/927069927069Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency UltrasonographyXiaohui Wang0Liang Chen1Weiwei Liu2Benli Su3Yuhong Zhang4Department of Ultrasound, Huiqiao VIP and International Medical Centre, Nanfang Hospital, Southern Medical University, Guangzhou 510515, ChinaDepartment of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, ChinaLibrary of Dalian Medical University, Dalian 116044, ChinaDepartment of Endocrinology, Second Affiliated Hospital of Dalian Medical University, Dalian 116023, ChinaDepartment of Diagnostic Ultrasound, Second Affiliated Hospital of Dalian Medical University, 467 Zhongshan Road, Dalian 116023, ChinaThe aim of this study was to evaluate the diagnostic value of high-frequency ultrasonography in detecting atrophy of foot muscles in Chinese patients of type 2 diabetes mellitus (T2DM). Chinese patients of T2DM with (n=56) or without (n=50) diabetic peripheral neuropathy (DPN) and the control subjects (n=50) were enrolled. The nondominant foot of all subjects was examined with high-frequency ultrasonography. The transverse diameter, thickness, and cross-sectional area of the extensor digitorum brevis muscle (EDB) and the thickness of the muscles of the first interstitium (MILs) were measured. The results showed that the ultrasonographic transverse diameter, thickness, and cross-sectional area of EDB and the thickness of MILs in patients of T2DM with DPN were significantly smaller than those in patients of T2DM without DPN (all P<0.01) and those in the control subjects (all P<0.01). The transverse diameter and cross-sectional area of the EDB and thickness of MILs in patients of T2DM without DPN were significantly smaller than those of the control subjects (all P<0.01). In conclusion, the atrophy of foot muscle in Chinese T2DM patients can be detected by high-frequency ultrasonography. Notably, ultrasonography may detect early atrophy of foot muscles in patients without DPN.http://dx.doi.org/10.1155/2014/927069 |
| spellingShingle | Xiaohui Wang Liang Chen Weiwei Liu Benli Su Yuhong Zhang Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography Journal of Diabetes Research |
| title | Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography |
| title_full | Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography |
| title_fullStr | Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography |
| title_full_unstemmed | Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography |
| title_short | Early Detection of Atrophy of Foot Muscles in Chinese Patients of Type 2 Diabetes Mellitus by High-Frequency Ultrasonography |
| title_sort | early detection of atrophy of foot muscles in chinese patients of type 2 diabetes mellitus by high frequency ultrasonography |
| url | http://dx.doi.org/10.1155/2014/927069 |
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