Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish.

<h4>Background</h4>Melanoma is the most aggressive and lethal form of skin cancer. Because of the increasing incidence and high lethality of melanoma, animal models for continuously observing melanoma formation and progression as well as for testing pharmacological agents are needed.<...

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Main Authors: Cristina Santoriello, Elisa Gennaro, Viviana Anelli, Martin Distel, Amanda Kelly, Reinhard W Köster, Adam Hurlstone, Marina Mione
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015170&type=printable
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