Genetic variants in immune mediators as potential molecular biomarkers for oral cancer evaluation: Insights from a systematic revaluation by computational analyses and Bayesian approaches

Genetic variants in immune mediators as potential molecular biomarkers for oral cancer evaluation: Insights from a systematic revaluation by computational analyses and Bayesian approaches

Background: Oral cancer is a complex disease in which genetic variations in immune mediator play a relevant role in its pathophysiology. This study aimed at assessing the level of false-positive rates on meta-analytic data on genetic variations in immune mediator genes related with oral cancer risk....

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Main Authors: Juliana Campos Botelho, Samuel Arcebispo Brasileiro, André Victor Oliveira Monteiro, Alessandro Luiz Araújo Bentes Leal, Naum Neves da Costa dos Santos, Gabrielly Ribeiro Alves, Reyce Santos Koga, Haline Alves da Silva, José Rogério Souza Monteiro, Denis Vieira Gomes Ferreira, Adenilson Leão Pereira, Ana Carolina Alves de Oliveira, Márcia Socorro Silva Lima Duarte, Felipe Rodolfo Pereira da Silva
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Oral Oncology Reports
Subjects:
Oral neoplasms
Cytokine
Risk factors
Alleles
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906025000172
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