Wide field imaging biomarkers: A different perspective

Wide field retinal imaging has emerged as a transformative technology over the last few decades, revolutionizing our ability to visualize the intricate landscape of the retina. By capturing expansive retinal areas, these techniques offer a panoramic view going beyond traditional imaging methods. In...

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Main Authors: Sakshi Shiromani, Niveditha Pattathil, Elham Sadeghi, Netan Choudhry, Jay Chhablani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Taiwan Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/tjo.TJO-D-24-00125
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author Sakshi Shiromani
Niveditha Pattathil
Elham Sadeghi
Netan Choudhry
Jay Chhablani
author_facet Sakshi Shiromani
Niveditha Pattathil
Elham Sadeghi
Netan Choudhry
Jay Chhablani
author_sort Sakshi Shiromani
collection DOAJ
description Wide field retinal imaging has emerged as a transformative technology over the last few decades, revolutionizing our ability to visualize the intricate landscape of the retina. By capturing expansive retinal areas, these techniques offer a panoramic view going beyond traditional imaging methods. In this review, we explore the significance of retinal imaging-based biomarkers to help diagnose ocular and systemic conditions. We discuss quantitative biomarkers, including ischemic index, nonperfusion area and more, and their application in diabetic retinopathy, central retinal vein occlusion, neurodegenerative diseases, and more. In addition, we outline qualitative biomarkers such as choroidal venous hyperpermeability and intervortex anastomoses. The role of wide field fundus autofluorescence in assessing hereditary retinal diseases is also emphasized. Standardized imaging procedures, professional collaboration, and validation across a range of clinical circumstances are necessary for the effective use of these biomarkers. They have the potential to transform disease identification, risk assessment, and customize therapy.
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id doaj-art-024d1e1fbb604087a4bbbcc941ecb5f6
institution Kabale University
issn 2211-5056
2211-5072
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Taiwan Journal of Ophthalmology
spelling doaj-art-024d1e1fbb604087a4bbbcc941ecb5f62025-01-14T15:50:25ZengWolters Kluwer Medknow PublicationsTaiwan Journal of Ophthalmology2211-50562211-50722024-12-0114451051810.4103/tjo.TJO-D-24-00125Wide field imaging biomarkers: A different perspectiveSakshi ShiromaniNiveditha PattathilElham SadeghiNetan ChoudhryJay ChhablaniWide field retinal imaging has emerged as a transformative technology over the last few decades, revolutionizing our ability to visualize the intricate landscape of the retina. By capturing expansive retinal areas, these techniques offer a panoramic view going beyond traditional imaging methods. In this review, we explore the significance of retinal imaging-based biomarkers to help diagnose ocular and systemic conditions. We discuss quantitative biomarkers, including ischemic index, nonperfusion area and more, and their application in diabetic retinopathy, central retinal vein occlusion, neurodegenerative diseases, and more. In addition, we outline qualitative biomarkers such as choroidal venous hyperpermeability and intervortex anastomoses. The role of wide field fundus autofluorescence in assessing hereditary retinal diseases is also emphasized. Standardized imaging procedures, professional collaboration, and validation across a range of clinical circumstances are necessary for the effective use of these biomarkers. They have the potential to transform disease identification, risk assessment, and customize therapy.https://journals.lww.com/10.4103/tjo.TJO-D-24-00125biomarkersqualitative biomarkersquantitative biomarkersretinal imagingwide field
spellingShingle Sakshi Shiromani
Niveditha Pattathil
Elham Sadeghi
Netan Choudhry
Jay Chhablani
Wide field imaging biomarkers: A different perspective
Taiwan Journal of Ophthalmology
biomarkers
qualitative biomarkers
quantitative biomarkers
retinal imaging
wide field
title Wide field imaging biomarkers: A different perspective
title_full Wide field imaging biomarkers: A different perspective
title_fullStr Wide field imaging biomarkers: A different perspective
title_full_unstemmed Wide field imaging biomarkers: A different perspective
title_short Wide field imaging biomarkers: A different perspective
title_sort wide field imaging biomarkers a different perspective
topic biomarkers
qualitative biomarkers
quantitative biomarkers
retinal imaging
wide field
url https://journals.lww.com/10.4103/tjo.TJO-D-24-00125
work_keys_str_mv AT sakshishiromani widefieldimagingbiomarkersadifferentperspective
AT nivedithapattathil widefieldimagingbiomarkersadifferentperspective
AT elhamsadeghi widefieldimagingbiomarkersadifferentperspective
AT netanchoudhry widefieldimagingbiomarkersadifferentperspective
AT jaychhablani widefieldimagingbiomarkersadifferentperspective