The role of LGR4 in bone metabolism and tumor bone metastasis

The role of LGR4 in bone metabolism and tumor bone metastasis

The Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4) is a member of the G protein-coupled receptor family and plays an important role in bone metabolism and tumor bone metastasis. LGR4 affects bone metabolism by regulating the differentiation and activity of osteoblasts and osteocl...

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Bibliographic Details
Main Authors: Jiawang Huang, Yucheng Jin, Zhigang Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
LGR4
bone metabolism
bone metastasis
osteoclasts
osteoblasts
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1541601/full
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