Functional connectivity of the nucleus accumbens predicts clinical course in medication adherent and non-adherent adult ADHD

Functional connectivity of the nucleus accumbens predicts clinical course in medication adherent and non-adherent adult ADHD

Abstract Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that persists into adulthood, contributing to a negative trajectory characterized by worsening symptoms, impaired daily functioning, and reduced quality of life over time. We studied seed-based functional conne...

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Bibliographic Details
Main Authors: Ahmed Zaher, Jan Leonards, Andreas Reif, Oliver Grimm
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
ADHD
Functional connectivity
Nucleus accumbens
Insular cortex
Methylphenidate
Reward system
Online Access:https://doi.org/10.1038/s41598-025-96780-3
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