Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging
Purpose. The increased use of magnetic resonance imaging (MRI) has resulted in reports of incidental abnormal bone marrow (BM) signal. Our goal was to determine the evaluation of an incidental abnormal BM signal on MRI and the prevalence of a subsequent oncologic diagnosis. Methods. We conducted a r...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/380814 |
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| _version_ | 1832558009121767424 |
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| author | Gunjan L. Shah Aaron S. Rosenberg Jamie Jarboe Andreas Klein Furha Cossor |
| author_facet | Gunjan L. Shah Aaron S. Rosenberg Jamie Jarboe Andreas Klein Furha Cossor |
| author_sort | Gunjan L. Shah |
| collection | DOAJ |
| description | Purpose. The increased use of magnetic resonance imaging (MRI) has resulted in reports of incidental abnormal bone marrow (BM) signal. Our goal was to determine the evaluation of an incidental abnormal BM signal on MRI and the prevalence of a subsequent oncologic diagnosis. Methods. We conducted a retrospective cohort study of patients over age 18 undergoing MRI between May 2005 and October 2010 at Tufts Medical Center (TMC) with follow-up through November 2013. The electronic medical record was queried to determine imaging site, reason for scan, evaluation following radiology report, and final diagnosis. Results. 49,678 MRIs were done with 110 patients meeting inclusion criteria. Twenty two percent underwent some evaluation, most commonly a complete blood count, serum protein electrophoresis, or bone scan. With median follow-up of 41 months, 6% of patients were diagnosed with malignancies including multiple myeloma, non-Hodgkins lymphoma, metastatic non-small cell lung cancer, and metastatic adenocarcinoma. One patient who had not undergone evaluation developed breast cancer 24 months after the MRI. Conclusions. Incidentally noted abnormal or heterogeneous bone marrow signal on MRI was not inconsequential and should prompt further evaluation. |
| format | Article |
| id | doaj-art-02315498e51c4c44a6eead5e14e0db97 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-02315498e51c4c44a6eead5e14e0db972025-02-03T01:33:26ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/380814380814Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance ImagingGunjan L. Shah0Aaron S. Rosenberg1Jamie Jarboe2Andreas Klein3Furha Cossor4Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, P.O. Box 298, New York, NY 10065, USADivision of Hematology/Oncology, UC Davis Comprehensive Cancer Center, 4501 X Street, Suite 3016, Sacramento, CA 95817, USAGraves Gilbert Clinic, 201 Park Street, Bowling Green, KY 42102, USATufts Medical Center, 800 Washington Street, P.O. Box 245, Boston, MA 02111, USALahey Hospital & Medical Center, 41 Mall Road, Burlington, MA 01805, USAPurpose. The increased use of magnetic resonance imaging (MRI) has resulted in reports of incidental abnormal bone marrow (BM) signal. Our goal was to determine the evaluation of an incidental abnormal BM signal on MRI and the prevalence of a subsequent oncologic diagnosis. Methods. We conducted a retrospective cohort study of patients over age 18 undergoing MRI between May 2005 and October 2010 at Tufts Medical Center (TMC) with follow-up through November 2013. The electronic medical record was queried to determine imaging site, reason for scan, evaluation following radiology report, and final diagnosis. Results. 49,678 MRIs were done with 110 patients meeting inclusion criteria. Twenty two percent underwent some evaluation, most commonly a complete blood count, serum protein electrophoresis, or bone scan. With median follow-up of 41 months, 6% of patients were diagnosed with malignancies including multiple myeloma, non-Hodgkins lymphoma, metastatic non-small cell lung cancer, and metastatic adenocarcinoma. One patient who had not undergone evaluation developed breast cancer 24 months after the MRI. Conclusions. Incidentally noted abnormal or heterogeneous bone marrow signal on MRI was not inconsequential and should prompt further evaluation.http://dx.doi.org/10.1155/2014/380814 |
| spellingShingle | Gunjan L. Shah Aaron S. Rosenberg Jamie Jarboe Andreas Klein Furha Cossor Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging The Scientific World Journal |
| title | Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging |
| title_full | Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging |
| title_fullStr | Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging |
| title_full_unstemmed | Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging |
| title_short | Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging |
| title_sort | incidence and evaluation of incidental abnormal bone marrow signal on magnetic resonance imaging |
| url | http://dx.doi.org/10.1155/2014/380814 |
| work_keys_str_mv | AT gunjanlshah incidenceandevaluationofincidentalabnormalbonemarrowsignalonmagneticresonanceimaging AT aaronsrosenberg incidenceandevaluationofincidentalabnormalbonemarrowsignalonmagneticresonanceimaging AT jamiejarboe incidenceandevaluationofincidentalabnormalbonemarrowsignalonmagneticresonanceimaging AT andreasklein incidenceandevaluationofincidentalabnormalbonemarrowsignalonmagneticresonanceimaging AT furhacossor incidenceandevaluationofincidentalabnormalbonemarrowsignalonmagneticresonanceimaging |