Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy

Objective. Contractility of gallbladder is known to be decreased in fatty gallbladder diseases. However, clinical estimation data about this relationship is still lacking. The aim of this study was to investigate the association between steatocholecystitis and contractility of gallbladder. Methods....

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Main Authors: Chang Seok Bang, Yong Sub Lee, Jai Hoon Yoon, Youn Jeong Kim, Jin Bong Kim, Dong Joon Kim
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/730930
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author Chang Seok Bang
Yong Sub Lee
Jai Hoon Yoon
Youn Jeong Kim
Jin Bong Kim
Dong Joon Kim
author_facet Chang Seok Bang
Yong Sub Lee
Jai Hoon Yoon
Youn Jeong Kim
Jin Bong Kim
Dong Joon Kim
author_sort Chang Seok Bang
collection DOAJ
description Objective. Contractility of gallbladder is known to be decreased in fatty gallbladder diseases. However, clinical estimation data about this relationship is still lacking. The aim of this study was to investigate the association between steatocholecystitis and contractility of gallbladder. Methods. Patients with cholecystitis (steatocholecystitis versus nonsteatocholecystitis) who underwent cholescintigraphy before cholecystectomy were retrospectively evaluated in a single teaching hospital of Korea. The association of steatocholecystitis with contractility of gallbladder, measured by preoperative cholescintigraphy, was assessed by univariable and multivariable analysis. Results. A total of 432 patients were finally enrolled (steatocholecystitis versus nonsteatocholecystitis; 75 versus 357, calculous versus acalculous cholecystitis; 316 versus 116). In the multivariable analysis, age (OR: 0.94, 95% CI: 0.90–0.99, P=0.01) and total serum cholesterol (OR: 1.02, 95% CI: 1.01–1.04, P=0.04) were related to steatocholecystitis in patients with acalculous cholecystitis. Only age (OR: 0.97, 95% CI: 0.94–0.99, P=0.004) was significantly related to steatocholecystitis in patients with calculous cholecystitis. However, ejection fraction of gallbladder reflecting contractility measured by cholescintigraphy was not related to steatocholecystitis irrespective of presence of gallbladder stone in patients with cholecystitis. Conclusion. Ejection fraction of gallbladder measured by cholescintigraphy cannot be used for the detection or confirmation of steatocholecystitis.
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spelling doaj-art-022c30a84e8e477e941fe9b7d0a3addb2025-08-20T03:22:27ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/730930730930Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by CholescintigraphyChang Seok Bang0Yong Sub Lee1Jai Hoon Yoon2Youn Jeong Kim3Jin Bong Kim4Dong Joon Kim5Department of Internal Medicine, Hallym University College of Medicine, 153 Gyo-dong, Chuncheon 200703, Republic of KoreaDepartment of Internal Medicine, Hallym University College of Medicine, 153 Gyo-dong, Chuncheon 200703, Republic of KoreaDepartment of Internal Medicine, Hallym University College of Medicine, 153 Gyo-dong, Chuncheon 200703, Republic of KoreaDepartment of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Republic of KoreaDepartment of Internal Medicine, Hallym University College of Medicine, 153 Gyo-dong, Chuncheon 200703, Republic of KoreaDepartment of Internal Medicine, Hallym University College of Medicine, 153 Gyo-dong, Chuncheon 200703, Republic of KoreaObjective. Contractility of gallbladder is known to be decreased in fatty gallbladder diseases. However, clinical estimation data about this relationship is still lacking. The aim of this study was to investigate the association between steatocholecystitis and contractility of gallbladder. Methods. Patients with cholecystitis (steatocholecystitis versus nonsteatocholecystitis) who underwent cholescintigraphy before cholecystectomy were retrospectively evaluated in a single teaching hospital of Korea. The association of steatocholecystitis with contractility of gallbladder, measured by preoperative cholescintigraphy, was assessed by univariable and multivariable analysis. Results. A total of 432 patients were finally enrolled (steatocholecystitis versus nonsteatocholecystitis; 75 versus 357, calculous versus acalculous cholecystitis; 316 versus 116). In the multivariable analysis, age (OR: 0.94, 95% CI: 0.90–0.99, P=0.01) and total serum cholesterol (OR: 1.02, 95% CI: 1.01–1.04, P=0.04) were related to steatocholecystitis in patients with acalculous cholecystitis. Only age (OR: 0.97, 95% CI: 0.94–0.99, P=0.004) was significantly related to steatocholecystitis in patients with calculous cholecystitis. However, ejection fraction of gallbladder reflecting contractility measured by cholescintigraphy was not related to steatocholecystitis irrespective of presence of gallbladder stone in patients with cholecystitis. Conclusion. Ejection fraction of gallbladder measured by cholescintigraphy cannot be used for the detection or confirmation of steatocholecystitis.http://dx.doi.org/10.1155/2015/730930
spellingShingle Chang Seok Bang
Yong Sub Lee
Jai Hoon Yoon
Youn Jeong Kim
Jin Bong Kim
Dong Joon Kim
Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy
Gastroenterology Research and Practice
title Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy
title_full Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy
title_fullStr Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy
title_full_unstemmed Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy
title_short Clinical Relationship between Steatocholecystitis and Gallbladder Contractility Measured by Cholescintigraphy
title_sort clinical relationship between steatocholecystitis and gallbladder contractility measured by cholescintigraphy
url http://dx.doi.org/10.1155/2015/730930
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