Current Concepts on Gastric Carcinoid Tumors
Gastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms that are closely linked to chronic atrophic ga...
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Wiley
2012-01-01
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Series: | Gastroenterology Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2012/287825 |
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author | George C. Nikou Theodoros P. Angelopoulos |
author_facet | George C. Nikou Theodoros P. Angelopoulos |
author_sort | George C. Nikou |
collection | DOAJ |
description | Gastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms that are closely linked to chronic atrophic gastritis. Type II which accounts for 5–10 %, is associated with Zollinger-Ellison syndrome and often occurs in the context of multiple endocrine neoplasia type 1. Type III, finally, represents 15–25% of gastric carcinoids and is characterized by a far more aggressive course. The optimal clinical approach to GCs remains to be elucidated, depending upon type, size, and number of carcinoids. While there is universal agreement about the surgical treatment of type III GCs, current options for type I and II include simple surveillance, endoscopic polypectomy, surgical excision associated with or without surgical antrectomy, or total gastrectomy. Moreover, the introduction of somatostatin analogues could represent another therapeutic option. |
format | Article |
id | doaj-art-022a083173d941d485a4b753c79f1a38 |
institution | Kabale University |
issn | 1687-6121 1687-630X |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Gastroenterology Research and Practice |
spelling | doaj-art-022a083173d941d485a4b753c79f1a382025-02-03T01:07:53ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/287825287825Current Concepts on Gastric Carcinoid TumorsGeorge C. Nikou0Theodoros P. Angelopoulos1Section of Gastrointestinal Neuroendocrinology, First Department of Propaedeutic Internal Medicine, Laiko Hospital, University of Athens Medical School, Agiou Thoma 17, Goudi, 11527 Athens, GreeceSection of Gastrointestinal Neuroendocrinology, First Department of Propaedeutic Internal Medicine, Laiko Hospital, University of Athens Medical School, Agiou Thoma 17, Goudi, 11527 Athens, GreeceGastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms that are closely linked to chronic atrophic gastritis. Type II which accounts for 5–10 %, is associated with Zollinger-Ellison syndrome and often occurs in the context of multiple endocrine neoplasia type 1. Type III, finally, represents 15–25% of gastric carcinoids and is characterized by a far more aggressive course. The optimal clinical approach to GCs remains to be elucidated, depending upon type, size, and number of carcinoids. While there is universal agreement about the surgical treatment of type III GCs, current options for type I and II include simple surveillance, endoscopic polypectomy, surgical excision associated with or without surgical antrectomy, or total gastrectomy. Moreover, the introduction of somatostatin analogues could represent another therapeutic option.http://dx.doi.org/10.1155/2012/287825 |
spellingShingle | George C. Nikou Theodoros P. Angelopoulos Current Concepts on Gastric Carcinoid Tumors Gastroenterology Research and Practice |
title | Current Concepts on Gastric Carcinoid Tumors |
title_full | Current Concepts on Gastric Carcinoid Tumors |
title_fullStr | Current Concepts on Gastric Carcinoid Tumors |
title_full_unstemmed | Current Concepts on Gastric Carcinoid Tumors |
title_short | Current Concepts on Gastric Carcinoid Tumors |
title_sort | current concepts on gastric carcinoid tumors |
url | http://dx.doi.org/10.1155/2012/287825 |
work_keys_str_mv | AT georgecnikou currentconceptsongastriccarcinoidtumors AT theodorospangelopoulos currentconceptsongastriccarcinoidtumors |