Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML

Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML

Abstract Background Acute myeloid leukemia (AML) is a highly heterogeneous disease characterized by complex genetic and molecular features that contribute to poor prognosis and low cure rates. Therefore, identifying novel therapeutic targets is crucial for improving treatment efficacy and patient su...

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Bibliographic Details
Main Authors: Zhibin Xie, Yang Xia, Zhongyu Li, Mengmeng Zhang, Yuanyuan Tan, Yuqing Han, Meng Wang, Pingping Zhang, Jiajia Li
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
CDK9
Acute myeloid leukemia
Biomarkers
Immune infiltration
Prognosis
Online Access:https://doi.org/10.1007/s12672-025-02841-4
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