Elucidation of Antimicrobials and Biofilm Inhibitors Derived from a Polyacetylene Core

Elucidation of Antimicrobials and Biofilm Inhibitors Derived from a Polyacetylene Core

The development of new antibiotics with unique mechanisms of action is paramount to combating the growing threat of antibiotic resistance. Recently, based on inspiration from natural products, an asymmetrical polyacetylene core structure was examined for its bioactivity and found to have differentia...

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Bibliographic Details
Main Authors: Tyler L. Skeen, Rebekah L. Gresham, Katherine A. Agamaite, Olivia M. Molz, Isabelle F. Westlake, Sage M. Kregenow, Al K. Romero, Brian M. Flood, Lauren E. Mazur, Robert J. Hinkle, Douglas D. Young
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
antibiotics
alkynes
biofilms
structure–activity relationships
Glaser–Hay reaction
Online Access:https://www.mdpi.com/1420-3049/29/24/5945
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