Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor
Paclitaxel nanoparticles are a compound with unique anticancer effects. Its mechanism of action is to prevent tumor rupture by stabilizing tumor proteins, while preventing cell division, leading to cell death, thereby inhibiting the spread of lung tumors. This article aims to study the treatment of...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2020/8823915 |
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| _version_ | 1832553443331407872 |
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| author | Di Hu YiMin Yang |
| author_facet | Di Hu YiMin Yang |
| author_sort | Di Hu |
| collection | DOAJ |
| description | Paclitaxel nanoparticles are a compound with unique anticancer effects. Its mechanism of action is to prevent tumor rupture by stabilizing tumor proteins, while preventing cell division, leading to cell death, thereby inhibiting the spread of lung tumors. This article aims to study the treatment of lung tumors with paclitaxel nanoparticles assisted by tennis rehabilitation training. In this paper, paclitaxel nanoparticles were prepared by a solvent displacement method, and their particle size and morphology were measured. The TA2 series of experimental rats were selected to establish animal lung tumor models, and they were randomly divided into 5 groups: local injection of saline, porphyrin, and low-, medium-, and high-dose paclitaxel nanoparticles for treatment. The experimental results in this paper show that the average particle size of the paclitaxel nanoparticles prepared in the experiment is about 153,54 nm. Each treatment group inhibited tumor development to varying degrees. Among them, the inhibitory volume rate of paclitaxel nanoparticles in the middle- and high-dose groups was significantly higher than that in the paclitaxel treatment group, indicating that paclitaxel nanoparticles can release drugs slowly. |
| format | Article |
| id | doaj-art-0214bd08867446eb8f6afd3cc3bd503e |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-0214bd08867446eb8f6afd3cc3bd503e2025-02-03T05:53:53ZengWileyJournal of Chemistry2090-90632090-90712020-01-01202010.1155/2020/88239158823915Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung TumorDi Hu0YiMin Yang1School of Sports Institute, Wuhan Business University, Wuhan 430056, Hubei, ChinaSchool of International Tennis Academy, Wuhan Sports University, Wuhan 430079, Hubei, ChinaPaclitaxel nanoparticles are a compound with unique anticancer effects. Its mechanism of action is to prevent tumor rupture by stabilizing tumor proteins, while preventing cell division, leading to cell death, thereby inhibiting the spread of lung tumors. This article aims to study the treatment of lung tumors with paclitaxel nanoparticles assisted by tennis rehabilitation training. In this paper, paclitaxel nanoparticles were prepared by a solvent displacement method, and their particle size and morphology were measured. The TA2 series of experimental rats were selected to establish animal lung tumor models, and they were randomly divided into 5 groups: local injection of saline, porphyrin, and low-, medium-, and high-dose paclitaxel nanoparticles for treatment. The experimental results in this paper show that the average particle size of the paclitaxel nanoparticles prepared in the experiment is about 153,54 nm. Each treatment group inhibited tumor development to varying degrees. Among them, the inhibitory volume rate of paclitaxel nanoparticles in the middle- and high-dose groups was significantly higher than that in the paclitaxel treatment group, indicating that paclitaxel nanoparticles can release drugs slowly.http://dx.doi.org/10.1155/2020/8823915 |
| spellingShingle | Di Hu YiMin Yang Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor Journal of Chemistry |
| title | Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor |
| title_full | Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor |
| title_fullStr | Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor |
| title_full_unstemmed | Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor |
| title_short | Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor |
| title_sort | tennis rehabilitation training assisted paclitaxel nanoparticles in treatment of lung tumor |
| url | http://dx.doi.org/10.1155/2020/8823915 |
| work_keys_str_mv | AT dihu tennisrehabilitationtrainingassistedpaclitaxelnanoparticlesintreatmentoflungtumor AT yiminyang tennisrehabilitationtrainingassistedpaclitaxelnanoparticlesintreatmentoflungtumor |