Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis
Pegaspargase is used to treat acute lymphocytic leukemia (ALL). Pegaspargase definitely has its benefits in treating ALL; however we cannot lose sight of one of its very rare but potentially deadly complications, acute pancreatitis. Clinicians should monitor triglycerides while the patient is on tre...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/753062 |
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| _version_ | 1832558148050747392 |
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| author | Neil Vyas Rafael Ching Companioni Melik Tiba Hassan Alkhawam Aaron Walfish |
| author_facet | Neil Vyas Rafael Ching Companioni Melik Tiba Hassan Alkhawam Aaron Walfish |
| author_sort | Neil Vyas |
| collection | DOAJ |
| description | Pegaspargase is used to treat acute lymphocytic leukemia (ALL). Pegaspargase definitely has its benefits in treating ALL; however we cannot lose sight of one of its very rare but potentially deadly complications, acute pancreatitis. Clinicians should monitor triglycerides while the patient is on treatment with Pegaspargase and suspect acute pancreatitis if the patient develops abdominal pain. If pancreatitis occurs, therapy should be stopped immediately and not reinstituted. For patients with hypertriglyceridemia without pancreatitis, discontinuation of therapy should be considered. |
| format | Article |
| id | doaj-art-0204e1bff8da49b99492fd0c2cfbce97 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-0204e1bff8da49b99492fd0c2cfbce972025-02-03T01:32:59ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362015-01-01201510.1155/2015/753062753062Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal PancreatitisNeil Vyas0Rafael Ching Companioni1Melik Tiba2Hassan Alkhawam3Aaron Walfish4Department of Medicine, Icahn School of Medicine at Mount Sinai (Elmhurst), 79-01 Broadway, Queens, NY 11373, USADepartment of Gastroenterology, Elmhurst Hospital Center, 79-01 Broadway, Queens, NY 11373, USADepartment of Gastroenterology, Elmhurst Hospital Center, 79-01 Broadway, Queens, NY 11373, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai (Elmhurst), 79-01 Broadway, Queens, NY 11373, USADepartment of Gastroenterology, Elmhurst Hospital Center, 79-01 Broadway, Queens, NY 11373, USAPegaspargase is used to treat acute lymphocytic leukemia (ALL). Pegaspargase definitely has its benefits in treating ALL; however we cannot lose sight of one of its very rare but potentially deadly complications, acute pancreatitis. Clinicians should monitor triglycerides while the patient is on treatment with Pegaspargase and suspect acute pancreatitis if the patient develops abdominal pain. If pancreatitis occurs, therapy should be stopped immediately and not reinstituted. For patients with hypertriglyceridemia without pancreatitis, discontinuation of therapy should be considered.http://dx.doi.org/10.1155/2015/753062 |
| spellingShingle | Neil Vyas Rafael Ching Companioni Melik Tiba Hassan Alkhawam Aaron Walfish Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis Case Reports in Gastrointestinal Medicine |
| title | Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis |
| title_full | Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis |
| title_fullStr | Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis |
| title_full_unstemmed | Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis |
| title_short | Pegaspargase Induced Hypertriglyceridemia Resulting in Severe Fatal Pancreatitis |
| title_sort | pegaspargase induced hypertriglyceridemia resulting in severe fatal pancreatitis |
| url | http://dx.doi.org/10.1155/2015/753062 |
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