Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial
Research suggests that inflammation is an important mediator in the pathophysiology of anxiety disorders. In addition, women are more likely to develop an anxiety and depression disorder, in comorbidity with a wide spectrum of diseases related to the immune system. In recent years, hydrogen-rich wat...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Open Medical Publishing
2022-05-01
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| Series: | Health Psychology Research |
| Online Access: | https://doi.org/10.52965/001c.35468 |
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| author | Ana Belén Fernández-Serrano Francisco José Moya-Faz Cesar Augusto Giner Alegría Juan Carlos Fernández Rodríguez Jose Francisco Soriano Guilabert Martín del Toro Mellado |
| author_facet | Ana Belén Fernández-Serrano Francisco José Moya-Faz Cesar Augusto Giner Alegría Juan Carlos Fernández Rodríguez Jose Francisco Soriano Guilabert Martín del Toro Mellado |
| author_sort | Ana Belén Fernández-Serrano |
| collection | DOAJ |
| description | Research suggests that inflammation is an important mediator in the pathophysiology of anxiety disorders. In addition, women are more likely to develop an anxiety and depression disorder, in comorbidity with a wide spectrum of diseases related to the immune system. In recent years, hydrogen-rich water has emerged as a promising therapeutic strategy to prevent and intervene in stress-related disorders, due to its antioxidant and anti-inflammatory properties. The present study aims to analyze the effects of psychological treatment and a hydrogen-rich drink on the severity of anxiety and depression, pro-inflammatory cytokine levels, the cortisol awakening response, and general health state in a sample of women with panic disorder. This is a completely randomized, placebo-controlled study. The treatment group simultaneously received psychological treatment and 1.5 L of hydrogenated water for three months, compared to the control group that received psychological treatment and placebo. The results show that the treatment group was not significantly better than the control group. But there was a further reduction in measured pro-inflammatory cytokine scores, improving body pain and physical health. When between-group treatment effects were removed, psychological treatment significantly decreased measured variables, including cytokines and cortisol. The results support the presence of a maladaptive inflammatory process in women with panic disorder. |
| format | Article |
| id | doaj-art-01fa9d2de3294c1e81b78a1171d68cd6 |
| institution | Kabale University |
| issn | 2420-8124 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | Open Medical Publishing |
| record_format | Article |
| series | Health Psychology Research |
| spelling | doaj-art-01fa9d2de3294c1e81b78a1171d68cd62025-02-11T20:30:35ZengOpen Medical PublishingHealth Psychology Research2420-81242022-05-01102Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trialAna Belén Fernández-SerranoFrancisco José Moya-FazCesar Augusto Giner AlegríaJuan Carlos Fernández RodríguezJose Francisco Soriano GuilabertMartín del Toro MelladoResearch suggests that inflammation is an important mediator in the pathophysiology of anxiety disorders. In addition, women are more likely to develop an anxiety and depression disorder, in comorbidity with a wide spectrum of diseases related to the immune system. In recent years, hydrogen-rich water has emerged as a promising therapeutic strategy to prevent and intervene in stress-related disorders, due to its antioxidant and anti-inflammatory properties. The present study aims to analyze the effects of psychological treatment and a hydrogen-rich drink on the severity of anxiety and depression, pro-inflammatory cytokine levels, the cortisol awakening response, and general health state in a sample of women with panic disorder. This is a completely randomized, placebo-controlled study. The treatment group simultaneously received psychological treatment and 1.5 L of hydrogenated water for three months, compared to the control group that received psychological treatment and placebo. The results show that the treatment group was not significantly better than the control group. But there was a further reduction in measured pro-inflammatory cytokine scores, improving body pain and physical health. When between-group treatment effects were removed, psychological treatment significantly decreased measured variables, including cytokines and cortisol. The results support the presence of a maladaptive inflammatory process in women with panic disorder.https://doi.org/10.52965/001c.35468 |
| spellingShingle | Ana Belén Fernández-Serrano Francisco José Moya-Faz Cesar Augusto Giner Alegría Juan Carlos Fernández Rodríguez Jose Francisco Soriano Guilabert Martín del Toro Mellado Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial Health Psychology Research |
| title | Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial |
| title_full | Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial |
| title_fullStr | Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial |
| title_full_unstemmed | Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial |
| title_short | Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial |
| title_sort | effects of hydrogen water and psychological treatment in a sample of women with panic disorder a randomized and controlled clinical trial |
| url | https://doi.org/10.52965/001c.35468 |
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