Local delivery of dinutuximab from lyophilized silk fibroin foams for treatment of an orthotopic neuroblastoma model
Abstract Immunotherapy targeting GD2 is a primary treatment for patients with high‐risk neuroblastoma. Dinutuximab is a monoclonal antibody with great clinical promise but is limited by side effects such as severe pain. Local delivery has emerged as a potential mechanism to deliver higher doses of t...
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| Main Authors: | Kimberly J. Ornell, Jordan S. Taylor, Jasmine Zeki, Naohiko Ikegaki, Hiroyuki Shimada, Jeannine M. Coburn, Bill Chiu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-04-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.2936 |
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