Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence
Xiaolin Bu,1,* Liwei Feng,2,* Jing Guo,3 Rongzhu Yu,2 Xinling Bi4 1Laboratory of Laser and Medical Innovation Application, Department of Dermatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China; 2School of Gongli Hospital Medical Technolo...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-07-01
|
| Series: | Clinical, Cosmetic and Investigational Dermatology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/development-of-a-cutaneous-horn-on-a-lower-extremity-with-granuloma-an-peer-reviewed-fulltext-article-CCID |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849716225240727552 |
|---|---|
| author | Bu X Feng L Guo J Yu R Bi X |
| author_facet | Bu X Feng L Guo J Yu R Bi X |
| author_sort | Bu X |
| collection | DOAJ |
| description | Xiaolin Bu,1,* Liwei Feng,2,* Jing Guo,3 Rongzhu Yu,2 Xinling Bi4 1Laboratory of Laser and Medical Innovation Application, Department of Dermatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China; 2School of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, People’s Republic of China; 3Postgraduate Training Base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, People’s Republic of China; 4Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xinling Bi, Department of Dermatology, Changhai Hospital, Naval Medical University, 168 Changhai Road, YangPu District, Shanghai, People’s Republic of China, Email bixinling@163.comAbstract: A 65-year-old Asian male presented with a circular skin lesion on the flexor aspect of the right calf that first appeared at age 13 and gradually expanded peripherally. Six months prior to presentation, a dark brown, horn-like keratotic lesion with a hard texture emerged on the annular lesion, growing progressively without pain or pruritus. The cutaneous horn was surgically excised, and the annular lesion underwent biopsy. Pathological findings revealed abundant mucin in dermal collagen, dense histiocyte infiltration, and focal mild collagen degeneration, confirming a diagnosis of granuloma annulare complicated by a cutaneous horn.Keywords: cutaneous horn, granuloma annulare, keratotic |
| format | Article |
| id | doaj-art-01e681af9c574ee5a0c73b35fec79be1 |
| institution | DOAJ |
| issn | 1178-7015 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj-art-01e681af9c574ee5a0c73b35fec79be12025-08-20T03:13:05ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152025-07-01Volume 18Issue 117531756104973Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-OccurrenceBu X0Feng L1Guo J2Yu R3Bi X4DermatologySchool of Gongli Hospital Medical Technology,Postgraduate training base at Shanghai Gongli HospitalSchool of Gongli Hospital Medical TechnologyDepartment of DermatologyXiaolin Bu,1,* Liwei Feng,2,* Jing Guo,3 Rongzhu Yu,2 Xinling Bi4 1Laboratory of Laser and Medical Innovation Application, Department of Dermatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China; 2School of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, People’s Republic of China; 3Postgraduate Training Base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, People’s Republic of China; 4Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xinling Bi, Department of Dermatology, Changhai Hospital, Naval Medical University, 168 Changhai Road, YangPu District, Shanghai, People’s Republic of China, Email bixinling@163.comAbstract: A 65-year-old Asian male presented with a circular skin lesion on the flexor aspect of the right calf that first appeared at age 13 and gradually expanded peripherally. Six months prior to presentation, a dark brown, horn-like keratotic lesion with a hard texture emerged on the annular lesion, growing progressively without pain or pruritus. The cutaneous horn was surgically excised, and the annular lesion underwent biopsy. Pathological findings revealed abundant mucin in dermal collagen, dense histiocyte infiltration, and focal mild collagen degeneration, confirming a diagnosis of granuloma annulare complicated by a cutaneous horn.Keywords: cutaneous horn, granuloma annulare, keratotichttps://www.dovepress.com/development-of-a-cutaneous-horn-on-a-lower-extremity-with-granuloma-an-peer-reviewed-fulltext-article-CCIDCutaneous horngranuloma annularekeratotic |
| spellingShingle | Bu X Feng L Guo J Yu R Bi X Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence Clinical, Cosmetic and Investigational Dermatology Cutaneous horn granuloma annulare keratotic |
| title | Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence |
| title_full | Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence |
| title_fullStr | Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence |
| title_full_unstemmed | Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence |
| title_short | Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence |
| title_sort | development of a cutaneous horn on a lower extremity with granuloma annulare a rare co occurrence |
| topic | Cutaneous horn granuloma annulare keratotic |
| url | https://www.dovepress.com/development-of-a-cutaneous-horn-on-a-lower-extremity-with-granuloma-an-peer-reviewed-fulltext-article-CCID |
| work_keys_str_mv | AT bux developmentofacutaneoushornonalowerextremitywithgranulomaannulareararecooccurrence AT fengl developmentofacutaneoushornonalowerextremitywithgranulomaannulareararecooccurrence AT guoj developmentofacutaneoushornonalowerextremitywithgranulomaannulareararecooccurrence AT yur developmentofacutaneoushornonalowerextremitywithgranulomaannulareararecooccurrence AT bix developmentofacutaneoushornonalowerextremitywithgranulomaannulareararecooccurrence |