Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic?
It was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. METHOD: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic...
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Thieme Revinter Publicações
2011-12-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700011&lng=en&tlng=en |
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| author | Sofia Rocha Arnaldo Pires Joana Gomes João Rocha Filipa Sousa João Pinho Margarida Rodrigues Carla Ferreira Álvaro Machado Ricardo Maré João Ramalho Fontes |
| author_facet | Sofia Rocha Arnaldo Pires Joana Gomes João Rocha Filipa Sousa João Pinho Margarida Rodrigues Carla Ferreira Álvaro Machado Ricardo Maré João Ramalho Fontes |
| author_sort | Sofia Rocha |
| collection | DOAJ |
| description | It was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. METHOD: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic (NCE). National Institutes of Health Stroke Scale (NIHSS) and modified Rankin scale were compared. RESULTS: The mean age was 67.4±12.01 and 53.8% were male. The mean NIHSS was: 14 (admission), 9 (24 h) and 6 (discharge), similar in subgroups. The difference between NIHSS at admission and 24 hours was 4.17±4.92 (CE: 4.08±4.71; NCE: 4.27±5.17, p=0.900) and at admission and discharge there was an average difference of 6.74±5.58 (CE: 6.97±5.68; NCE: 6.49±5.49, p=0.622). The mRS at discharge and 3 months was not significantly different by subtype, although individuals whose event was NCE are more independent at 3 months. CONCLUSION: Ours findings argue against a specific paper of IT in CE. It can result from heterogeneity of NCE group. |
| format | Article |
| id | doaj-art-01de0769e99943bcaef4e1661b4059b4 |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-01de0769e99943bcaef4e1661b4059b42025-08-20T03:22:30ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272011-12-0169690590910.1590/S0004-282X2011000700011S0004-282X2011000700011Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic?Sofia Rocha0Arnaldo Pires1Joana Gomes2João Rocha3Filipa Sousa4João Pinho5Margarida Rodrigues6Carla Ferreira7Álvaro Machado8Ricardo Maré9João Ramalho Fontes10Braga HospitalInternal Medicine DepartmentPorto Medicine UniversityBraga HospitalBraga HospitalBraga HospitalBraga HospitalBraga HospitalBraga HospitalBraga HospitalBraga HospitalIt was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. METHOD: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic (NCE). National Institutes of Health Stroke Scale (NIHSS) and modified Rankin scale were compared. RESULTS: The mean age was 67.4±12.01 and 53.8% were male. The mean NIHSS was: 14 (admission), 9 (24 h) and 6 (discharge), similar in subgroups. The difference between NIHSS at admission and 24 hours was 4.17±4.92 (CE: 4.08±4.71; NCE: 4.27±5.17, p=0.900) and at admission and discharge there was an average difference of 6.74±5.58 (CE: 6.97±5.68; NCE: 6.49±5.49, p=0.622). The mRS at discharge and 3 months was not significantly different by subtype, although individuals whose event was NCE are more independent at 3 months. CONCLUSION: Ours findings argue against a specific paper of IT in CE. It can result from heterogeneity of NCE group.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700011&lng=en&tlng=encardioembolismoacidente vascular cerebraltrombólise |
| spellingShingle | Sofia Rocha Arnaldo Pires Joana Gomes João Rocha Filipa Sousa João Pinho Margarida Rodrigues Carla Ferreira Álvaro Machado Ricardo Maré João Ramalho Fontes Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? Arquivos de Neuro-Psiquiatria cardioembolismo acidente vascular cerebral trombólise |
| title | Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? |
| title_full | Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? |
| title_fullStr | Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? |
| title_full_unstemmed | Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? |
| title_short | Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? |
| title_sort | intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non cardioembolic |
| topic | cardioembolismo acidente vascular cerebral trombólise |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700011&lng=en&tlng=en |
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