Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol
Introduction Varicocele (VC) is a common clinical disease in andrology. Among a number of ways for VC treatment, surgery is the most common one, but the measurable benefit of surgical repair was slight. A growing exploration of complementary therapies has been conducted in clinical research on acupu...
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BMJ Publishing Group
2022-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/12/e063381.full |
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| author | Jing Ding Miaomiao Sun Sijia Wang Qiang Lv Rongchen Lu Hongshuo Shi Jiangnan Chen Chenyao Wang Jianjun Ren Guangming Zhou Zhian Tang |
| author_facet | Jing Ding Miaomiao Sun Sijia Wang Qiang Lv Rongchen Lu Hongshuo Shi Jiangnan Chen Chenyao Wang Jianjun Ren Guangming Zhou Zhian Tang |
| author_sort | Jing Ding |
| collection | DOAJ |
| description | Introduction Varicocele (VC) is a common clinical disease in andrology. Among a number of ways for VC treatment, surgery is the most common one, but the measurable benefit of surgical repair was slight. A growing exploration of complementary therapies has been conducted in clinical research on acupuncture for VC, but there is no relevant systematic review and meta-analysis to assess the efficacy and safety of acupuncture for VC.Methods and analysis All relevant publications published from database inception through August 2022 will be searched in three English-language databases (Embase, CENTRAL, MEDLINE) and four Chinese-language databases (China National Knowledge Infrastructure, China Science and Technology Journal Database, Chinese Biomedical Literature Database and Wanfang Data). Randomised controlled trials in English and Chinese concerned with acupuncture for patients with VC will be included. The input clinical data will be processed by the Review Manager software (RevMan). The literature will be appraised with the Cochrane Collaboration risk of bias tool. The Grading of Recommendations Assessment, Development and Evaluation system (GRADE system) will be used to evaluate the quality of evidence.Ethics and dissemination This study is a secondary study based on clinical studies so it does not relate to any individual patient information or infringe the rights of participants. Hence no ethical approval is required. The results will be reported in peer-reviewed journals or disseminated at relevant conferences.PROSPERO registration number CRD42022316005. |
| format | Article |
| id | doaj-art-01db1bc8ce9142389536ed61b445b2a1 |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-01db1bc8ce9142389536ed61b445b2a12025-08-20T02:27:11ZengBMJ Publishing GroupBMJ Open2044-60552022-12-01121210.1136/bmjopen-2022-063381Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocolJing Ding0Miaomiao Sun1Sijia Wang2Qiang Lv3Rongchen Lu4Hongshuo Shi5Jiangnan Chen6Chenyao Wang7Jianjun Ren8Guangming Zhou9Zhian Tang10Department of Traditional Chinese Medicine, Yixing People`s Hospital, Yixing, Jiangsu, ChinaDepartment of Neurology and Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland1 Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi`an, Shaanxi, ChinaDepartment of Cardiology, Anzhen Hospital, Beijing, ChinaCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, ChinaDepartment of Traditional Chinese Medicine, Yixing People`s Hospital, Yixing, Jiangsu, ChinaDepartment of Traditional Chinese Medicine, Yixing People`s Hospital, Yixing, Jiangsu, ChinaDepartment of Otolaryngology-Head & Neck Surgery, Sichuan University West China Hospital, Chengdu, ChinaDepartment of Traditional Chinese Medicine, Yixing People`s Hospital, Yixing, Jiangsu, ChinaDepartment of Traditional Chinese Medicine, Yixing People`s Hospital, Yixing, Jiangsu, ChinaIntroduction Varicocele (VC) is a common clinical disease in andrology. Among a number of ways for VC treatment, surgery is the most common one, but the measurable benefit of surgical repair was slight. A growing exploration of complementary therapies has been conducted in clinical research on acupuncture for VC, but there is no relevant systematic review and meta-analysis to assess the efficacy and safety of acupuncture for VC.Methods and analysis All relevant publications published from database inception through August 2022 will be searched in three English-language databases (Embase, CENTRAL, MEDLINE) and four Chinese-language databases (China National Knowledge Infrastructure, China Science and Technology Journal Database, Chinese Biomedical Literature Database and Wanfang Data). Randomised controlled trials in English and Chinese concerned with acupuncture for patients with VC will be included. The input clinical data will be processed by the Review Manager software (RevMan). The literature will be appraised with the Cochrane Collaboration risk of bias tool. The Grading of Recommendations Assessment, Development and Evaluation system (GRADE system) will be used to evaluate the quality of evidence.Ethics and dissemination This study is a secondary study based on clinical studies so it does not relate to any individual patient information or infringe the rights of participants. Hence no ethical approval is required. The results will be reported in peer-reviewed journals or disseminated at relevant conferences.PROSPERO registration number CRD42022316005.https://bmjopen.bmj.com/content/12/12/e063381.full |
| spellingShingle | Jing Ding Miaomiao Sun Sijia Wang Qiang Lv Rongchen Lu Hongshuo Shi Jiangnan Chen Chenyao Wang Jianjun Ren Guangming Zhou Zhian Tang Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol BMJ Open |
| title | Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol |
| title_full | Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol |
| title_fullStr | Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol |
| title_full_unstemmed | Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol |
| title_short | Safety and efficacy of acupuncture for varicocele-induced male infertility: a systematic review protocol |
| title_sort | safety and efficacy of acupuncture for varicocele induced male infertility a systematic review protocol |
| url | https://bmjopen.bmj.com/content/12/12/e063381.full |
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