A TB40/E-derived human cytomegalovirus genome with an intact US-gene region and a self-excisable BAC cassette for immunological research

A TB40/E-derived human cytomegalovirus genome with an intact US-gene region and a self-excisable BAC cassette for immunological research

For immunological research on the human cytomegalovirus (HCMV), a virus that combines the broad cell tropism of clinical isolates, efficient replication in cell culture, the complete set of MHC-I modulator genes, and suitability for genetic engineering is desired. Here, we aimed to generate a geneti...

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Bibliographic Details
Main Authors: Kerstin Laib Sampaio, Anja Weyell, Narmadha Subramanian, Zeguang Wu, Christian Sinzger
Format: Article
Language:English
Published: Taylor & Francis Group 2017-11-01
Series:BioTechniques
Subjects:
HCMV
TB40/E
self-excisable BAC cassette
US genes
MHC-I
Online Access:https://www.future-science.com/doi/10.2144/000114606
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