Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.

Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.

We have characterized the biological functions of the chromatin remodeling protein Bptf (Bromodomain PHD-finger Transcription Factor), the largest subunit of NURF (Nucleosome Remodeling Factor) in a mammal. Bptf mutants manifest growth defects at the post-implantation stage and are reabsorbed by E8....

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Main Authors: Joseph Landry, Alexei A Sharov, Yulan Piao, Lioudmila V Sharova, Hua Xiao, Eileen Southon, Jennifer Matta, Lino Tessarollo, Ying E Zhang, Minoru S H Ko, Michael R Kuehn, Terry P Yamaguchi, Carl Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000241&type=printable
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