Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells

Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells

Abstract Background The blood-brain barrier (BBB) expresses transporters, receptors, and tight junction proteins that regulate the exchange of substances between the blood and brain. The differences in the expression of these proteins in the BBB among different species and cultured BBB model cells s...

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Bibliographic Details
Main Authors: Haruka Kumabe, Takeshi Masuda, Shingo Ito, Tomomi Furihata, Akiko Toda, Masayuki Mogi, Norie Araki, Sumio Ohtsuki
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Fluids and Barriers of the CNS
Subjects:
Brain microvessels
Proteomics
Mouse
Monkey
Human
Species differences
Online Access:https://doi.org/10.1186/s12987-025-00650-z
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