A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population.

A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population.

SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis. Nonetheless, the effects of SIRT1 variants on MI risk remain poorly understood. Here we aimed to investigate the influence...

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Bibliographic Details
Main Authors: Jie Cheng, Miook Cho, Jin-ming Cen, Meng-yun Cai, Shun Xu, Ze-wei Ma, Xinguang Liu, Xi-li Yang, Can Chen, Yousin Suh, Xing-dong Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0115339&type=printable
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