125I inhibits the progression of cervical cancer by upregulating the HSF1/PU.1/SYK signaling pathway and consequently enhancing the apoptotic response mediated by ROS/USP7/P53
Abstract 125I (iodine-125) is a radioactive isotope commonly used in the treatment of cervical cancer, especially in brachytherapy. This study investigates the molecular mechanism by which 125I radiotherapy inhibits the progression of cervical cancer. C33A cervical cancer cells were subjected to irr...
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| Main Authors: | Xiaomei Fan, Xiaoliang Liang, Yunfeng Guo, Ge Jin, Dong Ming, Xingwei An |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-99214-2 |
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