The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats
The scope of our study was to investigate the changes in electrospun polylactic acid (PLA) fiber mats’ morphological, mechanical, and thermal properties in vitro. We electrospun two sets of PLA fiber mats with different average diameters, E6 (747 nm) and E10 (1263 nm). The degradation study of PLA e...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Fibers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6439/13/1/1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832588459642978304 |
|---|---|
| author | Kardo Khalid Abdullah Kolos Molnár |
| author_facet | Kardo Khalid Abdullah Kolos Molnár |
| author_sort | Kardo Khalid Abdullah |
| collection | DOAJ |
| description | The scope of our study was to investigate the changes in electrospun polylactic acid (PLA) fiber mats’ morphological, mechanical, and thermal properties in vitro. We electrospun two sets of PLA fiber mats with different average diameters, E6 (747 nm) and E10 (1263 nm). The degradation study of PLA electrospun fibers was carried out in phosphate-buffered saline solution at 37 °C to simulate conditions within the human system. The results reveal the thicker fibers (E10) degraded more rapidly than the E6 sample due to their different morphology. E10 showed a 29% reduction in diameter and a 41% weight loss, while E6 exhibited an 18% reduction in diameter and a 27.5% weight loss. E6’s Young’s modulus increased by 3.55 times, while E10’s rose by 2.23 times after 28 days of degradation, and the fibers became more rigid. E6 showed a more pronounced decrease in crystallinity compared with E10. Changes in electrospun fiber diameters and crystallinity greatly influence the degradation mechanism of PLA. |
| format | Article |
| id | doaj-art-01b0ec91ad2845b996ea4709c7b4598f |
| institution | Kabale University |
| issn | 2079-6439 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Fibers |
| spelling | doaj-art-01b0ec91ad2845b996ea4709c7b4598f2025-01-24T13:32:11ZengMDPI AGFibers2079-64392024-12-01131110.3390/fib13010001The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber MatsKardo Khalid Abdullah0Kolos Molnár1Department of Polymer Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, HungaryDepartment of Polymer Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, HungaryThe scope of our study was to investigate the changes in electrospun polylactic acid (PLA) fiber mats’ morphological, mechanical, and thermal properties in vitro. We electrospun two sets of PLA fiber mats with different average diameters, E6 (747 nm) and E10 (1263 nm). The degradation study of PLA electrospun fibers was carried out in phosphate-buffered saline solution at 37 °C to simulate conditions within the human system. The results reveal the thicker fibers (E10) degraded more rapidly than the E6 sample due to their different morphology. E10 showed a 29% reduction in diameter and a 41% weight loss, while E6 exhibited an 18% reduction in diameter and a 27.5% weight loss. E6’s Young’s modulus increased by 3.55 times, while E10’s rose by 2.23 times after 28 days of degradation, and the fibers became more rigid. E6 showed a more pronounced decrease in crystallinity compared with E10. Changes in electrospun fiber diameters and crystallinity greatly influence the degradation mechanism of PLA.https://www.mdpi.com/2079-6439/13/1/1electrospinningpolylactic acidpolymer degradationfiber mat |
| spellingShingle | Kardo Khalid Abdullah Kolos Molnár The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats Fibers electrospinning polylactic acid polymer degradation fiber mat |
| title | The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats |
| title_full | The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats |
| title_fullStr | The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats |
| title_full_unstemmed | The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats |
| title_short | The Influence of In Vitro Degradation on the Properties of Polylactic Acid Electrospun Fiber Mats |
| title_sort | influence of in vitro degradation on the properties of polylactic acid electrospun fiber mats |
| topic | electrospinning polylactic acid polymer degradation fiber mat |
| url | https://www.mdpi.com/2079-6439/13/1/1 |
| work_keys_str_mv | AT kardokhalidabdullah theinfluenceofinvitrodegradationonthepropertiesofpolylacticacidelectrospunfibermats AT kolosmolnar theinfluenceofinvitrodegradationonthepropertiesofpolylacticacidelectrospunfibermats AT kardokhalidabdullah influenceofinvitrodegradationonthepropertiesofpolylacticacidelectrospunfibermats AT kolosmolnar influenceofinvitrodegradationonthepropertiesofpolylacticacidelectrospunfibermats |