Multi-omics analysis of two rat models reveals potential role of vesicle transport and autophagy in right ventricular remodeling

Multi-omics analysis of two rat models reveals potential role of vesicle transport and autophagy in right ventricular remodeling

Abstract Right ventricular failure as a severe consequence of pulmonary arterial hypertension (PAH) is an independent risk factor for poor prognosis, although the pathogenesis of right ventricular remodeling (RVR) remains unclear. Exploring the shared molecular pathways and key molecules in the righ...

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Bibliographic Details
Main Authors: Yuhan Qin, Jing Zhang, Aiwei Wang, Wei Sun, Xiaohan Qin, Feng Qi, Yufei Wang, Le Du, Xiaoyan Liu, Haidan Sun, Zhengguang Guo, Xiaoxiao Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Proteome
Metabolome
Right ventricular remodeling
Vesicle transport
Autophagy
Online Access:https://doi.org/10.1038/s41598-025-98347-8
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